Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | PI4KA | P42356 | 1/20 | 0.32 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.32 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | PNP | P00491 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CDC7 | O00311 | 1/20 | 0.30 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11918991 | 0.76 | NUDT1 (0.36) | NUDT1ADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL2639251 | 0.75 | ADORA2A (0.37) | NUDT1ADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL29454410 | 0.72 | ADORA2A (0.61) | NUDT1ADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL42335 | 0.72 | ADORA2A (0.61) | NUDT1ADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL8823867 | 0.72 | ADORA2A (0.35) | NUDT1ADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL355788 | 0.71 | GSK3B (0.41) | PDPK1NUDT1ADORA2AADORA1CSF1R | |
| SCHEMBL10217115 | 0.71 | FFAR2 (0.36) | NUDT1ADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL9500277 | 0.71 | ENPP1 (0.40) | NUDT1 | |
| SCHEMBL29923950 | 0.71 | GSK3B (0.41) | PDPK1NUDT1ADORA2AADORA1CSF1R | |
| SCHEMBL6887345 | 0.69 | KDM4E (0.45) | MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0539487-A1 | ANTIVIRAL PHOSPHONO-ALKEN DERIVATIVES OF PURINES | BEECHAM GROUP PLC (GB) | 1993-05-05 | — | — | EP | disclosed |
| WO-1992001698-A1 | ANTIVIRAL PHOSPHONO-ALKEN DERIVATIVES OF PURINES | BEECHAM GROUP PLC (GB) | 1992-02-06 | — | — | WO | disclosed |