Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | GPR52 | Q9Y2T5 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504623 | 1.00 | ALOX5 (0.45) | ALOX5HDAC1HDAC6GPR52GAA | |
| SCHEMBL9504867 | 0.82 | GPR52 (0.48) | ALOX5GPR52KCNA3 | |
| SCHEMBL9504873 | 0.82 | GPR52 (0.48) | ALOX5GPR52KCNA3 | |
| SCHEMBL9504697 | 0.79 | PPARG (0.48) | HPGD | |
| SCHEMBL9504706 | 0.79 | PPARG (0.48) | HPGD | |
| SCHEMBL11019590 | 0.79 | PPARG (0.48) | HPGD | |
| SCHEMBL9506258 | 0.78 | PPARG (0.50) | HPGD | |
| SCHEMBL9506265 | 0.78 | PPARG (0.50) | HPGD | |
| SCHEMBL9508151 | 0.77 | TNNC1 (0.47) | THRATHRB | |
| SCHEMBL9508145 | 0.77 | TNNC1 (0.47) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161939-B1 | ARYLHYDROXAMATES | E.R. Squibb & Sons, Inc. (US) | 1993-07-21 | — | — | EP | disclosed |
| US-4607053-A | L2POXYGENASE INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1986-08-19 | — | — | US | disclosed |
| EP-0161939-A2 | Arylhydroxamates | E.R. Squibb & Sons, Inc. (US) | 1985-11-21 | — | — | EP | disclosed |