Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 7/20 | 0.53 |
| ▸ | METAP1 | P53582 | 5/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | LAP3 | P28838 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6479809 | 0.83 | IDO1 (0.52) | METAP2METAP1CTSLCTSBCTSS | |
| SCHEMBL8759874 | 0.82 | METAP2 (0.47) | METAP2METAP1CTSLCTSBCTSS | |
| Hydrochloric Acid SCHEMBL3825774 | 0.82 | IDO1 (0.51) | METAP2METAP1CTSLCTSBCTSS | |
| Hydrochloric Acid SCHEMBL7297833 | 0.82 | IDO1 (0.51) | METAP2METAP1CTSLCTSBCTSS | |
| SCHEMBL13017759 | 0.81 | CTSB (0.49) | METAP2METAP1CTSLCTSBCTSS | |
| SCHEMBL6473457 | 0.81 | IDO1 (0.53) | METAP2METAP1CTSLCTSBCTSS | |
| SCHEMBL7442293 | 0.81 | CTSB (0.49) | METAP2METAP1CTSLCTSBCTSS | |
| SCHEMBL5981841 | 0.81 | CTSB (0.49) | METAP2METAP1CTSLCTSBCTSS | |
| SCHEMBL10445626 | 0.81 | METAP2 (0.52) | METAP2METAP1CTSLCTSBCTSS | |
| SCHEMBL7300665 | 0.81 | METAP2 (0.47) | METAP2METAP1CTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045537-A | Treating Diseases Caused by Retroviruses | SANDOZ LTD. (CH) | 1991-09-03 | — | — | US | disclosed |