Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504847 | 0.88 | ALOX5 (0.55) | ALOX5HDAC1THRATHRBRCE1 | |
| SCHEMBL9504801 | 0.87 | THRA (0.58) | ALDH1A1MAPTTHRATHRB | |
| SCHEMBL9504638 | 0.85 | ALOX5 (0.64) | ALOX5HDAC1HDAC8RCE1HDAC6 | |
| SCHEMBL9504721 | 0.84 | THRA (0.63) | ALOX5ALDH1A1MAPTTHRATHRB | |
| SCHEMBL9508914 | 0.84 | THRA (0.56) | ALOX5ALDH1A1MAPTTHRATHRB | |
| SCHEMBL9506078 | 0.83 | ALOX5 (0.63) | ALOX5HDAC1MAPTTHRATHRB | |
| SCHEMBL16794763 | 0.82 | ALDH1A1 (0.58) | HDAC1ALDH1A1HPGDMAPTHDAC6 | |
| SCHEMBL9123942 | 0.80 | HPGD (0.48) | ALDH1A1HPGDMAPT | |
| SCHEMBL9506661 | 0.80 | HDAC1 (0.48) | ALOX5HDAC1MAPTTHRATHRB | |
| SCHEMBL9504787 | 0.79 | ALOX5 (0.50) | ALOX5HDAC1MAPTTHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161939-B1 | ARYLHYDROXAMATES | E.R. Squibb & Sons, Inc. (US) | 1993-07-21 | — | — | EP | disclosed |
| CN-1012500-B | Process for preparing aryl hydroxamates | SQUIBB & SONS INC (US) | 1991-05-01 | — | — | CN | disclosed |
| CN-85104470-A | The method for preparing arythydroxamtes | — | 1986-10-01 | — | — | CN | disclosed |
| US-4607053-A | L2POXYGENASE INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1986-08-19 | — | — | US | disclosed |
| EP-0161939-A2 | Arylhydroxamates | E.R. Squibb & Sons, Inc. (US) | 1985-11-21 | — | — | EP | disclosed |