Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.34 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504996 | 0.85 | CYP1A2 (0.37) | CYP1A2CYP3A4CYP2C19GAAP2RX1 | |
| SCHEMBL9818596 | 0.78 | MEN1 (0.36) | CYP1A2CYP3A4CYP2C19GAAP2RX1 | |
| SCHEMBL9738579 | 0.76 | PRKD3 (0.43) | — | |
| SCHEMBL9739910 | 0.76 | PDE4B (0.35) | CYP3A4CYP2C19GAAIGF1RKMT2A | |
| SCHEMBL10400918 | 0.75 | ALDH1A1 (0.35) | CYP1A2CYP3A4CYP2C19GAAKMT2A | |
| SCHEMBL9539862 | 0.74 | ALDH1A1 (0.35) | P2RX1KMT2AMEN1PDK1PDK2 | |
| SCHEMBL10517413 | 0.73 | ALDH1A1 (0.34) | CYP1A2CYP3A4CYP2C19P2RX1KMT2A | |
| SCHEMBL9818604 | 0.72 | NPC1 (0.43) | KMT2AMEN1ALDH1A1POLBNPC1 | |
| SCHEMBL10400826 | 0.72 | F2 (0.34) | P2RX1KMT2AMEN1MAPTPDK1 | |
| SCHEMBL10458605 | 0.72 | KMT2A (0.40) | CYP1A2CYP2C19KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337946-B1 | UREAS | CIBA-GEIGY AG (CH) | 1993-07-28 | — | — | EP | claimed |
| US-4999046-A | Herbicides and plant growth regulators, agricultural use | CIBA-GEIGY CORPORATION (US) | 1991-03-12 | — | — | US | claimed |
| EP-0337946-A1 | Ureas | CIBA-GEIGY AG (CH) | 1989-10-18 | — | — | EP | claimed |
| EP-0337946-B1 | UREAS | CIBA-GEIGY AG (CH) | 1993-07-28 | — | — | EP | disclosed |
| US-4999046-A | Herbicides and plant growth regulators, agricultural use | CIBA-GEIGY CORPORATION (US) | 1991-03-12 | — | — | US | disclosed |
| EP-0337946-A1 | Ureas | CIBA-GEIGY AG (CH) | 1989-10-18 | — | — | EP | disclosed |