Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | POLB | P06746 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9505019 | 0.85 | CYP1A2 (0.35) | CYP1A2CYP2C19CYP3A4GAALMNA | |
| SCHEMBL9535470 | 0.82 | SMN1; SMN2 (0.35) | CYP1A2CYP2C19LMNAALDH1A1POLB | |
| SCHEMBL9738579 | 0.80 | PRKD3 (0.43) | — | |
| SCHEMBL10401161 | 0.78 | SMN1; SMN2 (0.37) | LMNAALDH1A1POLBL3MBTL1HPGD | |
| SCHEMBL9538333 | 0.74 | TP53 (0.36) | CYP1A2CYP2C19GAALMNAALDH1A1 | |
| SCHEMBL9536816 | 0.74 | SMN1; SMN2 (0.35) | CYP1A2CYP2C19LMNAALDH1A1POLB | |
| SCHEMBL9737747 | 0.74 | PTGES (0.36) | GAAMAPTRXRARXRBRXRG | |
| SCHEMBL10400976 | 0.74 | SMN1; SMN2 (0.37) | LMNAALDH1A1POLBL3MBTL1HPGD | |
| SCHEMBL10400132 | 0.73 | MAPT (0.41) | CYP1A2CYP2C19CYP3A4LMNAALDH1A1 | |
| SCHEMBL9739376 | 0.72 | RBP4 (0.39) | CYP3A4ALDH1A1HPGDMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337946-B1 | UREAS | CIBA-GEIGY AG (CH) | 1993-07-28 | — | — | EP | claimed |
| US-4999046-A | Herbicides and plant growth regulators, agricultural use | CIBA-GEIGY CORPORATION (US) | 1991-03-12 | — | — | US | claimed |
| EP-0337946-A1 | Ureas | CIBA-GEIGY AG (CH) | 1989-10-18 | — | — | EP | claimed |
| EP-0337946-B1 | UREAS | CIBA-GEIGY AG (CH) | 1993-07-28 | — | — | EP | disclosed |
| US-4999046-A | Herbicides and plant growth regulators, agricultural use | CIBA-GEIGY CORPORATION (US) | 1991-03-12 | — | — | US | disclosed |
| EP-0337946-A1 | Ureas | CIBA-GEIGY AG (CH) | 1989-10-18 | — | — | EP | disclosed |