Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD3 | O94806 | 2/20 | 0.43 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.43 |
| ▸ | CLK2 | P49760 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 14/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | ACVR2B | Q13705 | 1/20 | 0.38 |
| ▸ | MYLK | Q15746 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | NLK | Q9UBE8 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504996 | 0.80 | CYP1A2 (0.37) | — | |
| SCHEMBL9738360 | 0.77 | MAPK14 (0.41) | PRKD3PRKD2CLK2DYRK1APIM2 | |
| SCHEMBL9739910 | 0.76 | PDE4B (0.35) | — | |
| SCHEMBL10400106 | 0.76 | PRKD3 (0.42) | PRKD3PRKD2CLK2DYRK1APIM2 | |
| SCHEMBL9737677 | 0.75 | MAPK14 (0.45) | PRKD3PRKD2CLK2DYRK1APIM2 | |
| SCHEMBL9739162 | 0.74 | MAPK14 (0.38) | PRKD3PRKD2CLK2DYRK1APIM2 | |
| SCHEMBL9737747 | 0.73 | PTGES (0.36) | MAPK14 | |
| SCHEMBL9739960 | 0.71 | HSP90AA1 (0.39) | PRKD3PRKD2CLK2DYRK1APIM2 | |
| SCHEMBL9737076 | 0.71 | MAPK14 (0.43) | MAPK14 | |
| SCHEMBL9739376 | 0.70 | RBP4 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5159078-A | Herbicides, plant growth regulator | CIBA-GEIGY CORPORATION (US) | 1992-10-27 | — | — | US | disclosed |
| US-4966622-A | HERBICIDES, PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1990-10-30 | — | — | US | disclosed |