Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 4/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9505403 | 0.86 | SMN1; SMN2 (0.51) | MTNR1BMTNR1APOLBNR4A1RAB9A | |
| SCHEMBL13652569 | 0.83 | MTNR1B (0.59) | MTNR1BMTNR1APOLBNR4A1RAB9A | |
| SCHEMBL9503172 | 0.78 | MTNR1A (0.38) | MTNR1BMTNR1AKMT2AMEN1ALDH1A1 | |
| SCHEMBL1141400 | 0.77 | MTNR1B (0.81) | MTNR1BMTNR1APOLBNR4A1RAB9A | |
| SCHEMBL1142037 | 0.76 | HTT (0.72) | MTNR1BMTNR1APOLBNR4A1RAB9A | |
| SCHEMBL10673426 | 0.75 | MTNR1B (0.53) | MTNR1BMTNR1APOLBNR4A1RAB9A | |
| SCHEMBL10970617 | 0.74 | RAB9A (0.85) | POLBNR4A1RAB9AGAAKMT2A | |
| SCHEMBL9503469 | 0.74 | MTNR1A (0.41) | MTNR1BMTNR1APOLBNR4A1RAB9A | |
| SCHEMBL10294097 | 0.73 | MTNR1B (0.58) | MTNR1BMTNR1APOLBNR4A1RAB9A | |
| SCHEMBL9795787 | 0.73 | MTNR1A (0.46) | MTNR1BMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328968-B1 | PROCESS FOR THE PREPARATION OF 4-ACYLAMINO-2-AMINO ALKOXY BENZENES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-05-12 | — | — | EP | disclosed |
| US-5047586-A | Process for the preparation of 4-acylamino-2-aminoalkoxybenzenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-09-10 | — | — | US | disclosed |
| EP-0328968-A2 | Process for the preparation of 4-acylamino-2-amino alkoxy benzenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-23 | — | — | EP | disclosed |