Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 10/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | OGG1 | O15527 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20885297 | 0.82 | LMNA (0.44) | MTNR1AMTNR1BTAAR1KDM4ENSD2 | |
| SCHEMBL9505261 | 0.78 | MTNR1B (0.52) | MTNR1AMTNR1BMEN1KMT2AALDH1A1 | |
| SCHEMBL4615206 | 0.77 | ALDH1A1 (0.40) | MTNR1AMTNR1BKDM4ENSD2ALDH1A1 | |
| SCHEMBL544377 | 0.76 | MTNR1A (0.49) | MTNR1AMTNR1BTAAR1ALDH1A1NPSR1 | |
| SCHEMBL65345 | 0.74 | MTNR1A (0.41) | MTNR1AMTNR1BKDM4ENSD2ALDH1A1 | |
| SCHEMBL9501614 | 0.73 | MTNR1A (0.37) | MTNR1AMTNR1BMEN1KMT2AKDM4E | |
| SCHEMBL13686326 | 0.73 | NPSR1 (0.50) | MTNR1AMTNR1BTAAR1MEN1KMT2A | |
| SCHEMBL9795773 | 0.72 | MTNR1A (0.56) | MTNR1AMTNR1B | |
| SCHEMBL16981249 | 0.72 | ACHE (0.47) | KMT2AALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL7651909 | 0.72 | TAAR1 (0.44) | MTNR1AMTNR1BTAAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328968-B1 | PROCESS FOR THE PREPARATION OF 4-ACYLAMINO-2-AMINO ALKOXY BENZENES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-05-12 | — | — | EP | disclosed |
| US-5047586-A | Process for the preparation of 4-acylamino-2-aminoalkoxybenzenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-09-10 | — | — | US | disclosed |