Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | AHR | P35869 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9505261 | 0.86 | MTNR1B (0.52) | SMN1; SMN2RAB9AALDH1A1MTNR1AMTNR1B | |
| SCHEMBL27588285 | 0.81 | ALDH1A1 (0.56) | SMN1; SMN2RAB9ANPC1ALDH1A1AHR | |
| SCHEMBL9504353 | 0.81 | RAB9A (0.65) | SMN1; SMN2RAB9ANPC1ALDH1A1AHR | |
| SCHEMBL17680726 | 0.81 | CA2 (0.58) | SMN1; SMN2RAB9ANPC1ALDH1A1MTNR1A | |
| SCHEMBL9503172 | 0.80 | MTNR1A (0.38) | SMN1; SMN2ALDH1A1MTNR1AMTNR1BMEN1 | |
| SCHEMBL19732837 | 0.75 | BRAF (0.64) | SMN1; SMN2RAB9ANPC1ALDH1A1AHR | |
| SCHEMBL11438891 | 0.75 | NR1H4 (0.62) | SMN1; SMN2RAB9ANPC1AHRMTNR1A | |
| SCHEMBL27420326 | 0.75 | SMN1; SMN2 (0.51) | SMN1; SMN2RAB9ANPC1ALDH1A1AHR | |
| SCHEMBL2000945 | 0.74 | KMT2A (0.63) | SMN1; SMN2RAB9ANPC1ALDH1A1AHR | |
| SCHEMBL11546092 | 0.74 | SMN1; SMN2 (0.68) | SMN1; SMN2RAB9ANPC1ALDH1A1AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328968-B1 | PROCESS FOR THE PREPARATION OF 4-ACYLAMINO-2-AMINO ALKOXY BENZENES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-05-12 | — | — | EP | disclosed |
| US-5047586-A | Process for the preparation of 4-acylamino-2-aminoalkoxybenzenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-09-10 | — | — | US | disclosed |
| EP-0328968-A2 | Process for the preparation of 4-acylamino-2-amino alkoxy benzenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-23 | — | — | EP | disclosed |