Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH5 | Q6P6C2 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9503892 | 0.86 | TSHR (0.51) | ALKBH5ALDH1A1KMT2AMEN1HTT | |
| SCHEMBL11469612 | 0.85 | ALKBH5 (0.46) | ALKBH5ALDH1A1KMT2AMEN1HTT | |
| SCHEMBL9507906 | 0.85 | ALKBH5 (0.44) | ALKBH5ALDH1A1KMT2AMEN1HTT | |
| SCHEMBL1734462 | 0.81 | CYP2C19 (0.43) | ALKBH5ALDH1A1KMT2AMEN1HTT | |
| SCHEMBL9505993 | 0.81 | ALDH1A1 (0.41) | ALKBH5ALDH1A1HTTMAPTKDM4E | |
| SCHEMBL19322447 | 0.80 | ALKBH5 (0.54) | ALKBH5ALDH1A1KMT2AMEN1HTT | |
| SCHEMBL10923063 | 0.77 | TSHR (0.49) | ALKBH5ALDH1A1KMT2AMEN1HTT | |
| SCHEMBL9505312 | 0.76 | ALKBH5 (1.00) | ALKBH5ALDH1A1KMT2AMAPTKDM4E | |
| SCHEMBL11218444 | 0.76 | CA2 (0.39) | ALKBH5ALDH1A1KMT2AMEN1HTT | |
| SCHEMBL8007070 | 0.74 | TSHR (0.49) | ALKBH5ALDH1A1KMT2AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0297397-B1 | PREPARATION OF DIAZO AND AZO COMPOUNDS | BAYER AG (DE) | 1993-08-04 | — | — | EP | disclosed |
| EP-0297397-A2 | Preparation of diazo and azo compounds | BAYER AG (DE) | 1989-01-04 | — | — | EP | disclosed |
| EP-0093306-B1 | METHODS FOR THE PREPARATION OF AZO COMPOUNDS, AND AZO COMPOUNDS | BAYER AG (DE) | 1986-09-24 | — | — | EP | disclosed |
| EP-0093306-A1 | Methods for the preparation of azo compounds, and azo compounds | BAYER AG (DE) | 1983-11-09 | — | — | EP | disclosed |