SCHEMBL9507906

SCHEMBL9507906

O=C(O)Oc1cc(=O)n(-c2ccc(Cl)c(Cl)c2)[nH]1

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALKBH5 Q6P6C2 9/20 0.44
KMT2A Q03164 3/20 0.41
ALDH1A1 P00352 3/20 0.41
MEN1 O00255 2/20 0.41
GAA P10253 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
MAPT P10636 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
KDM4E B2RXH2 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
NOTUM Q6P988 3/20 0.37
MME P08473 1/20 0.37
LDHA P00338 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
HTT P42858 1/20 0.35
GFER P55789 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9505315 0.85 ALKBH5 (0.61) ALKBH5KMT2AALDH1A1MEN1GAA
SCHEMBL11469612 0.83 ALKBH5 (0.46) ALKBH5KMT2AALDH1A1MEN1GAA
SCHEMBL9503892 0.80 TSHR (0.51) ALKBH5KMT2AALDH1A1MEN1GAA
SCHEMBL9505993 0.79 ALDH1A1 (0.41) ALKBH5ALDH1A1L3MBTL1MAPTSMN1; SMN2
SCHEMBL9507900 0.78 ALKBH5 (0.72) ALKBH5KMT2AALDH1A1MEN1GAA
SCHEMBL1734462 0.76 CYP2C19 (0.43) ALKBH5KMT2AALDH1A1MEN1GAA
SCHEMBL9338638 0.74 ALKBH5 (0.35) ALKBH5KMT2AALDH1A1MEN1GAA
SCHEMBL2484228 0.72 KMT2A (0.60) ALKBH5KMT2AALDH1A1MEN1GAA
SCHEMBL10923063 0.72 TSHR (0.49) ALKBH5KMT2AALDH1A1MEN1GAA
SCHEMBL11218444 0.71 CA2 (0.39) ALKBH5KMT2AALDH1A1MEN1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0297397-B1 PREPARATION OF DIAZO AND AZO COMPOUNDS BAYER AG (DE) 1993-08-04 EP disclosed
EP-0093306-B1 METHODS FOR THE PREPARATION OF AZO COMPOUNDS, AND AZO COMPOUNDS BAYER AG (DE) 1986-09-24 EP disclosed
EP-0093306-A1 Methods for the preparation of azo compounds, and azo compounds BAYER AG (DE) 1983-11-09 EP disclosed