SCHEMBL9505312

SCHEMBL9505312

O=C(O)c1cc(=O)n(-c2ccc(Cl)cc2)[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALKBH5 Q6P6C2 17/20 1.00
MME P08473 1/20 0.54
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50
MAPT P10636 1/20 0.50
KMT2A Q03164 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
TDP1 Q9NUW8 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11436522 0.85 ALKBH5 (0.74) ALKBH5MMEKDM4EALDH1A1MAPT
SCHEMBL11442141 0.85 ALKBH5 (0.74) ALKBH5MMEKDM4EALDH1A1MAPT
SCHEMBL693015 0.85 ALKBH5 (0.73) ALKBH5KDM4EALDH1A1MAPTKMT2A
SCHEMBL951472 0.84 ALKBH5 (0.73) ALKBH5ALDH1A1MAPT
SCHEMBL9507900 0.84 ALKBH5 (0.72) ALKBH5MMEKDM4EALDH1A1MAPT
SCHEMBL11300860 0.84 ALKBH5 (0.72) ALKBH5MMEKDM4EALDH1A1MAPT
SCHEMBL11774629 0.83 ALKBH5 (0.71) ALKBH5KDM4EALDH1A1MAPTKMT2A
SCHEMBL10787351 0.83 ALKBH5 (0.71) ALKBH5KDM4EALDH1A1MAPTKMT2A
SCHEMBL1265504 0.80 ALKBH5 (0.67) ALKBH5KDM4EALDH1A1MAPTKMT2A
SCHEMBL9505990 0.80 ALKBH5 (0.66) ALKBH5MMEKDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0297397-B1 PREPARATION OF DIAZO AND AZO COMPOUNDS BAYER AG (DE) 1993-08-04 EP disclosed
US-4942225-A Preparation of diazo and azo compounds using azidoformamidium salts BAYER AKTIENGESELLSCHAFT (DE) 1990-07-17 US disclosed
EP-0297397-A2 Preparation of diazo and azo compounds BAYER AG (DE) 1989-01-04 EP disclosed
EP-0093306-B1 METHODS FOR THE PREPARATION OF AZO COMPOUNDS, AND AZO COMPOUNDS BAYER AG (DE) 1986-09-24 EP disclosed
EP-0093306-A1 Methods for the preparation of azo compounds, and azo compounds BAYER AG (DE) 1983-11-09 EP disclosed