Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 8/20 | 0.36 |
| ▸ | CACNA1D | Q01668 | 6/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 5/20 | 0.36 |
| ▸ | CACNA1S | Q13698 | 5/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504261 | 0.81 | MGAM (0.66) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL7272515 | 0.68 | MGAM (0.56) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL11007622 | 0.65 | CACNA1C (0.58) | MAPTCACNA1CCACNA1DCACNA1FCACNA1S | |
| SCHEMBL7272519 | 0.65 | CACNA1C (0.53) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL9874899 | 0.64 | NR1I2 (0.61) | GAAMAPTCACNA1CCACNA1DCACNA1F | |
| SCHEMBL11373038 | 0.64 | CYP2C9 (0.57) | GAAMAPTCACNA1CCACNA1DCACNA1F | |
| SCHEMBL9502266 | 0.63 | MGAM (0.54) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL7265346 | 0.63 | CYP1A2 (0.80) | MAPTCACNA1CCACNA1DCACNA1FCACNA1S | |
| SCHEMBL9518606 | 0.63 | GAA (0.64) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL8680780 | 0.63 | ADORA3 (0.67) | MAPTCACNA1CCACNA1DCACNA1FCACNA1S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0458823-B1 | A PROCESS FOR PREPARATION OF ENANTIOMERICALLY PURE POLYSUBSTITUTED 1,4-DIHYDROPYRIDINES | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1993-10-13 | — | — | EP | disclosed |
| US-5245039-A | PROCESS FOR PREPARATION OF ENANTIOMERICALLY PURE POLYSUBSTITUTED 1,4-DIHYDROPYRIDINES | BOEHRINGER MANNHEIM ITALIA (IT) | 1993-09-14 | — | — | US | disclosed |
| WO-1990009376-A1 | A PROCESS FOR PREPARATION OF ENANTIOMERICALLY PURE POLYSUBSTITUTED 1,4-DIHYDROPYRIDINES | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1990-08-23 | — | — | WO | disclosed |