Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9501539 | 0.85 | PSIP1 (0.46) | PTGS2ALDH1A1L3MBTL1CETPSMN1; SMN2 | |
| SCHEMBL8091476 | 0.78 | PTGS2 (0.55) | PTGS2ALDH1A1KMT2APTGS1SMN1; SMN2 | |
| SCHEMBL9504735 | 0.76 | CYP19A1 (0.61) | PTGS2ALDH1A1KMT2APTGS1SMN1; SMN2 | |
| SCHEMBL11360737 | 0.76 | CETP (0.54) | ALDH1A1KMT2AL3MBTL1CETPSMN1; SMN2 | |
| SCHEMBL9502669 | 0.74 | CYP19A1 (0.60) | PTGS2ALDH1A1KMT2APTGS1SMN1; SMN2 | |
| SCHEMBL20495594 | 0.74 | MAOA (0.44) | ALDH1A1KMT2ACETPSMN1; SMN2 | |
| SCHEMBL30548748 | 0.74 | MAOA (0.44) | ALDH1A1KMT2ACETPSMN1; SMN2 | |
| SCHEMBL11353345 | 0.74 | CETP (0.55) | ALDH1A1KMT2AL3MBTL1CETPSMN1; SMN2 | |
| SCHEMBL11367064 | 0.74 | CETP (0.51) | ALDH1A1KMT2AL3MBTL1CETPSMN1; SMN2 | |
| SCHEMBL11359720 | 0.73 | CETP (0.54) | KMT2AL3MBTL1CETPSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0317332-B1 | SULFONANILIDE COMPOUNDS | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1993-05-19 | — | — | EP | disclosed |
| US-4885367-A | ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANALGESICS; SIDE EFFECT REDUCTION | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1989-12-05 | — | — | US | disclosed |
| EP-0317332-A2 | Sulfonanilide compounds | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1989-05-24 | — | — | EP | disclosed |