Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 10/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 10/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | BID | P55957 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10431544 | 0.69 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1CYP2C9CYP2C19KMT2A | |
| SCHEMBL9505649 | 0.69 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9560197 | 0.69 | CYSLTR2 (0.65) | CYSLTR2CYSLTR1KMT2ALTB4RBID | |
| SCHEMBL29090154 | 0.69 | CYSLTR2 (0.66) | CYSLTR2CYSLTR1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9504777 | 0.67 | CYSLTR2 (0.57) | CYSLTR2CYSLTR1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9504779 | 0.66 | CYSLTR2 (0.59) | CYSLTR2CYSLTR1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL10435204 | 0.65 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1BIDBCL2L1MCL1 | |
| SCHEMBL3242848 | 0.65 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1BIDBCL2L1MCL1 | |
| SCHEMBL6449278 | 0.64 | CYSLTR2 (0.44) | CYSLTR2CYSLTR1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9428890 | 0.64 | CYSLTR2 (0.50) | CYSLTR2CYSLTR1BIDBCL2L1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375348-B1 | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-06-23 | — | — | EP | claimed |