SCHEMBL2164909

SCHEMBL2164909

O=[N+]([O-])c1c(S(=O)(=O)O)sc2ccccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.43
LMNA P02545 3/20 0.43
KMT2A Q03164 3/20 0.43
HPGD P15428 2/20 0.43
MEN1 O00255 2/20 0.43
POLB P06746 1/20 0.43
S100A4 P26447 2/20 0.42
SMN1; SMN2 Q16637 3/20 0.40
HTT P42858 2/20 0.40
MAPK1 P28482 1/20 0.40
CYP3A4 P08684 1/20 0.40
ALDH1A1 P00352 4/20 0.38
KDM4E B2RXH2 3/20 0.38
RAB9A P51151 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
ALOX15 P16050 1/20 0.38
ATIC P31939 1/20 0.38
CYP2C19 P33261 1/20 0.38
HIF1A Q16665 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2164911 1.00 MAPT (0.43) MAPTLMNAKMT2AHPGDMEN1
SCHEMBL2165461 0.84 LMNA (0.43) MAPTLMNAKMT2AHPGDMEN1
SCHEMBL28932849 0.76 S100A4 (0.52) MAPTLMNAKMT2AHPGDMEN1
SCHEMBL788508 0.73 HSD11B1 (0.47) MAPTLMNAKMT2AMEN1POLB
SCHEMBL7116533 0.73 MCL1 (0.51) MAPTLMNAKMT2AMEN1POLB
SCHEMBL28769752 0.73 HPGD (0.50) MAPTLMNAKMT2AHPGDMEN1
SCHEMBL9506713 0.73 MAPT (0.50) MAPTLMNAKMT2AHPGDMEN1
SCHEMBL28556282 0.72 MCL1 (0.56) MAPTLMNAKMT2AHPGDMEN1
SCHEMBL28041851 0.71 S100A4 (0.50) LMNAKMT2AHPGDMEN1POLB
SCHEMBL9672404 0.71 S100A4 (0.50) LMNAKMT2AHPGDMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8906591-B2 Fluorine-free fused ring heteroaromatic photoacid generators and resist compositions containing the same INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2014-12-09 US disclosed
US-8906591-B2 Fluorine-free fused ring heteroaromatic photoacid generators and resist compositions containing the same INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2014-12-09 US disclosed
US-8906591-B2 Fluorine-free fused ring heteroaromatic photoacid generators and resist compositions containing the same INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2014-12-09 US disclosed
US-8883395-B2 Fluorine-free fused ring heteroaromatic photoacid generators and resist compositions containing the same INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2014-11-11 US disclosed
US-8883395-B2 Fluorine-free fused ring heteroaromatic photoacid generators and resist compositions containing the same INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2014-11-11 US disclosed
US-8883395-B2 Fluorine-free fused ring heteroaromatic photoacid generators and resist compositions containing the same INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2014-11-11 US disclosed
US-8871429-B2 Fluorine-free fused ring heteroaromatic photoacid generators and resist compositions containing the same INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2014-10-28 US disclosed
US-8871429-B2 Fluorine-free fused ring heteroaromatic photoacid generators and resist compositions containing the same INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2014-10-28 US disclosed
US-8871429-B2 Fluorine-free fused ring heteroaromatic photoacid generators and resist compositions containing the same INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2014-10-28 US disclosed
CN-102741747-B Fluorine-free fused ring heteroaromatic photoacid generators and resist compositions containing the same IBM 2014-09-10 CN disclosed
US-20130011788-A1 FLUORINE-FREE FUSED RING HETEROAROMATIC PHOTOACID GENERATORS AND RESIST COMPOSITIONS CONTAINING THE SAME INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-01-10 US disclosed
US-20130011787-A1 FLUORINE-FREE FUSED RING HETEROAROMATIC PHOTOACID GENERATORS AND RESIST COMPOSITIONS CONTAINING THE SAME INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-01-10 US disclosed
US-20130011790-A1 FLUORINE-FREE FUSED RING HETEROAROMATIC PHOTOACID GENERATORS AND RESIST COMPOSITIONS CONTAINING THE SAME INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-01-10 US disclosed
US-20130011790-A1 FLUORINE-FREE FUSED RING HETEROAROMATIC PHOTOACID GENERATORS AND RESIST COMPOSITIONS CONTAINING THE SAME INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-01-10 US disclosed
US-8343706-B2 Fluorine-free fused ring heteroaromatic photoacid generators and resist compositions containing the same INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-01-01 US disclosed
US-8343706-B2 Fluorine-free fused ring heteroaromatic photoacid generators and resist compositions containing the same INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-01-01 US disclosed
US-8343706-B2 Fluorine-free fused ring heteroaromatic photoacid generators and resist compositions containing the same INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-01-01 US disclosed
US-20110183259-A1 FLUORINE-FREE FUSED RING HETEROAROMATIC PHOTOACID GENERATORS AND RESIST COMPOSITIONS CONTAINING THE SAME INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2011-07-28 US disclosed
US-20110183259-A1 FLUORINE-FREE FUSED RING HETEROAROMATIC PHOTOACID GENERATORS AND RESIST COMPOSITIONS CONTAINING THE SAME INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2011-07-28 US disclosed
WO-2011089033-A1 FLUORINE-FREE FUSED RING HETEROAROMATIC PHOTOACID GENERATORS AND RESIST COMPOSITIONS CONTAINING THE SAME INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2011-07-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130011787-A1 FLUORINE-FREE FUSED RING HETEROAROMATIC PHOTOACID GENERATORS AND RESIST COMPOSITIONS CONTAINING THE SAME ARF5, ARFGEF1, ARFGAP1 MAPT 3922/4885LMNA 4341/4885KMT2A 3004/4885
US-20130011790-A1 FLUORINE-FREE FUSED RING HETEROAROMATIC PHOTOACID GENERATORS AND RESIST COMPOSITIONS CONTAINING THE SAME ARF5, ARFGEF1, ARFGAP1 MAPT 3922/4885LMNA 4341/4885KMT2A 3004/4885
US-20110183259-A1 FLUORINE-FREE FUSED RING HETEROAROMATIC PHOTOACID GENERATORS AND RESIST COMPOSITIONS CONTAINING THE SAME ARF5, ARFGEF1, ARFGAP1 MAPT 3922/4885LMNA 4341/4885KMT2A 3004/4885
US-20130011788-A1 FLUORINE-FREE FUSED RING HETEROAROMATIC PHOTOACID GENERATORS AND RESIST COMPOSITIONS CONTAINING THE SAME ARF5, ARFGEF1, ARFGAP1 MAPT 3922/4885LMNA 4341/4885KMT2A 3004/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.