SCHEMBL9507584

SCHEMBL9507584

COc1cc(-c2ccc(N=Cc3ccccc3)c(OC)c2)ccc1N=Cc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1B1 Q16678 2/20 0.54
RORC P51449 1/20 0.50
ALDH1A1 P00352 6/20 0.47
CYP3A4 P08684 3/20 0.47
HPGD P15428 3/20 0.47
TDP1 Q9NUW8 2/20 0.47
MAPT P10636 4/20 0.44
KDM4E B2RXH2 4/20 0.44
CYP1A2 P05177 3/20 0.44
GAA P10253 3/20 0.44
CYP2C9 P11712 2/20 0.44
CYP2C19 P33261 2/20 0.44
LMNA P02545 2/20 0.44
CYP2D6 P10635 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
KMT2A Q03164 2/20 0.42
PKM P14618 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9507577 1.00 CYP1B1 (0.54) CYP1B1RORCALDH1A1CYP3A4HPGD
SCHEMBL11404198 0.85 CYP1B1 (0.65) CYP1B1RORCALDH1A1CYP3A4HPGD
SCHEMBL1643202 0.82 ALDH1A1 (0.48) CYP1B1ALDH1A1HPGDMAPTKDM4E
SCHEMBL1643205 0.82 ALDH1A1 (0.48) CYP1B1ALDH1A1HPGDMAPTKDM4E
SCHEMBL28610776 0.82 ALDH1A1 (0.48) CYP1B1ALDH1A1HPGDMAPTKDM4E
SCHEMBL5484284 0.78 CA2 (0.50) RORCALDH1A1HPGDMAPTKDM4E
SCHEMBL5484286 0.78 CA2 (0.50) RORCALDH1A1HPGDMAPTKDM4E
SCHEMBL10766481 0.77 CYP1B1 (0.45) CYP1B1CYP3A4CYP1A2CYP2C9CYP2C19
SCHEMBL27984216 0.75 NFE2L2 (0.54) CYP1B1ALDH1A1HPGDMAPTKDM4E
SCHEMBL30633421 0.74 SMN1; SMN2 (0.41) CYP1B1ALDH1A1HPGDMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0205083-B1 IMAGE FORMING METHOD AND TRANSFER RECORDING MEDIUM THEREFOR CANON KABUSHIKI KAISHA (JP) 1993-09-01 EP disclosed
EP-0261394-B1 IMAGE RECORDING APPARATUS CANON KABUSHIKI KAISHA (JP) 1993-08-11 EP disclosed
US-5015552-A Multilayer optical image recording process involving crosslinking, treatment with heat or light, transferring CANON KABUSHIKI KAISHA (JP) 1991-05-14 US disclosed
US-5005028-A Image forming method and transfer recording medium therefor CANON KABUSHIKI KAISHA (JP) 1991-04-02 US disclosed
US-4990931-A Image forming method and apparatus therefor CANON KABUSHIKI KAISHA (JP) 1991-02-05 US disclosed
US-4978968-A Image recording apparatus CANON KABUSHIKI KAISHA (JP) 1990-12-18 US disclosed
EP-0205083-A2 Image forming method and transfer recording medium therefor CANON KABUSHIKI KAISHA (JP) 1986-12-17 EP disclosed
US-4205988-A Photochromic method involving an aromatic amine ASAHI KASEI K. K. (JP) 1980-06-03 US disclosed