Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1643205 | 1.00 | ALDH1A1 (0.48) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL28610776 | 1.00 | ALDH1A1 (0.48) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL3272348 | 0.87 | GAA (0.57) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL27984216 | 0.87 | NFE2L2 (0.54) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL3663896 | 0.86 | KDM4E (0.47) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL16096675 | 0.86 | ROCK2 (0.46) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL16096676 | 0.86 | ROCK2 (0.46) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL30633421 | 0.83 | SMN1; SMN2 (0.41) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL9507584 | 0.82 | CYP1B1 (0.54) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL9507577 | 0.82 | CYP1B1 (0.54) | ALDH1A1KDM4EMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160272742-A1 | IRON COMPLEXES AND METHODS FOR POLYMERIZATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-09-22 | — | — | US | disclosed |
| US-9290591-B2 | Iron complexes and methods for polymerization | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-03-22 | — | — | US | disclosed |
| US-20140011971-A1 | IRON COMPLEXES AND METHODS FOR POLYMERIZATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-01-09 | — | — | US | disclosed |
| US-8530593-B2 | Catalyst compounds and use thereof | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-09-10 | — | — | US | disclosed |
| US-8530593-B2 | Catalyst compounds and use thereof | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-09-10 | — | — | US | disclosed |
| US-8530593-B2 | Catalyst compounds and use thereof | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-09-10 | — | — | US | disclosed |
| WO-2012109343-A2 | IRON COMPLEXES AND METHODS FOR POLYMERIZATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-08-16 | — | — | WO | disclosed |
| WO-2011056432-A2 | CATALYST COMPOUNDS AND USE THEREOF | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2011-05-12 | — | — | WO | disclosed |
| US-20110098431-A1 | Catalyst Compounds and Use Thereof | EXXONMOBIL CHEMICAL PATENTS INC. | 2011-04-28 | — | — | US | disclosed |
| US-20110098431-A1 | Catalyst Compounds and Use Thereof | EXXONMOBIL CHEMICAL PATENTS INC. | 2011-04-28 | — | — | US | disclosed |
| US-20110098431-A1 | Catalyst Compounds and Use Thereof | EXXONMOBIL CHEMICAL PATENTS INC. | 2011-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098431-A1 | Catalyst Compounds and Use Thereof | PAM, AAAS, PAOX | ALDH1A1 2448/4885KDM4E 3249/4885MEN1 4594/4885 |
| US-20160272742-A1 | IRON COMPLEXES AND METHODS FOR POLYMERIZATION | FTH1, TFRC, FDPS | ALDH1A1 3893/4885KDM4E 3606/4885MEN1 394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.