SCHEMBL9507755

SCHEMBL9507755

Cc1cc(C)nc(C(=O)O)c1.[NaH]

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.46
TSHR P16473 1/20 0.46
HIF1A Q16665 1/20 0.46
LCK P06239 1/20 0.46
TPMT P51580 1/20 0.43
MAPK1 P28482 2/20 0.42
ALDH1A1 P00352 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
GPR35 Q9HC97 2/20 0.42
NOS3 P29474 2/20 0.41
NOS2 P35228 2/20 0.41
NOS1 P29475 1/20 0.41
CTSA P10619 2/20 0.41
DAO P14920 1/20 0.41
HCAR2 Q8TDS4 1/20 0.41
IGFBP3 P17936 2/20 0.41
LMNA P02545 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
SORT1 Q99523 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL668136 0.98 ALOX15 (0.48) ALOX15TSHRHIF1ALCKTPMT
SCHEMBL14136412 0.86 ALOX15 (0.61) ALOX15TSHRHIF1ATPMTALDH1A1
Hydrochloric Acid SCHEMBL18640672 0.84 ALOX15 (0.58) ALOX15TSHRHIF1ATPMTALDH1A1
SCHEMBL875421 0.80 NOS3 (0.43) LCKMAPK1ALDH1A1SMN1; SMN2NOS3
Bicarbonate SCHEMBL9343614 0.79 NOS3 (0.50) LCKTPMTMAPK1ALDH1A1SMN1; SMN2
SCHEMBL4772052 0.78 ALOX15 (0.46) ALOX15TSHRHIF1AMAPK1ALDH1A1
SCHEMBL3112850 0.78 LMNA (0.48) LCKNOS3NOS2NOS1CTSA
SCHEMBL3686639 0.78 ALOX15 (0.71) ALOX15TSHRHIF1ATPMTMAPK1
SCHEMBL25222774 0.77 NOS2 (0.50) ALOX15TSHRHIF1ATPMTGPR35
SCHEMBL1424923 0.77 ALDH1A1 (0.47) ALOX15TSHRHIF1AMAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0272903-B1 PROCESS FOR PRODUCING A POLYARYLENE SULFIDE Tosoh Corporation (JP) 1993-07-21 EP claimed
US-4794163-A HIGH MOLECULAR WEIGHT, HEAT RESISTANCE TOSOH CORPORATION (JP) 1988-12-27 US claimed
EP-0272903-A2 Process for producing a polyarylene sulfide Tosoh Corporation (JP) 1988-06-29 EP claimed
EP-0272903-B1 PROCESS FOR PRODUCING A POLYARYLENE SULFIDE Tosoh Corporation (JP) 1993-07-21 EP disclosed
US-4794163-A HIGH MOLECULAR WEIGHT, HEAT RESISTANCE TOSOH CORPORATION (JP) 1988-12-27 US disclosed
EP-0272903-A2 Process for producing a polyarylene sulfide Tosoh Corporation (JP) 1988-06-29 EP disclosed