SCHEMBL9507841

SCHEMBL9507841

C=C(CC(=O)OCC1COC(=O)O1)C(=O)O

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
MGLL Q99685 5/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
MAPK1 P28482 1/20 0.33
RECQL P46063 1/20 0.32
LMNA P02545 1/20 0.32
POLB P06746 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10480854 0.88 ALDH1A1 (0.41) ALDH1A1MGLLL3MBTL1MAPK1RECQL
SCHEMBL24006695 0.82 ALDH1A1 (0.36) ALDH1A1MGLLL3MBTL1MAPK1RECQL
SCHEMBL13571814 0.81 RECQL (0.31) ALDH1A1RECQLSMN1; SMN2
SCHEMBL10480855 0.81 ALDH1A1 (0.40) ALDH1A1L3MBTL1MAPK1
SCHEMBL21301194 0.81 LMNA (0.44) ALDH1A1MGLLL3MBTL1LMNAPOLB
SCHEMBL14003899 0.80 LMNA (0.46) MGLLLMNAPOLB
SCHEMBL15356646 0.80 MGLL (0.37) MGLLL3MBTL1MAPK1LMNAPOLB
SCHEMBL13217160 0.80 LMNA (0.50) ALDH1A1MGLLLMNAPOLB
SCHEMBL394803 0.79 ALDH1A1 (0.53) ALDH1A1MGLL
SCHEMBL9644012 0.79 L3MBTL1 (0.38) ALDH1A1MGLLL3MBTL1MAPK1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0274721-B1 POLYMERS CONTAINING AMINO GROUPS, THEIR MANUFACTURE AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1993-09-15 EP claimed
EP-0274721-A2 Polymers containing amino groups, their manufacture and their use HOECHST AKTIENGESELLSCHAFT (DE) 1988-07-20 EP claimed
EP-0274721-B1 POLYMERS CONTAINING AMINO GROUPS, THEIR MANUFACTURE AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1993-09-15 EP disclosed
EP-0272664-B1 CURABLE MIXTURES AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1992-05-27 EP disclosed
EP-0274721-A2 Polymers containing amino groups, their manufacture and their use HOECHST AKTIENGESELLSCHAFT (DE) 1988-07-20 EP disclosed
EP-0272664-A2 Curable mixtures and their use HOECHST AKTIENGESELLSCHAFT (DE) 1988-06-29 EP disclosed