SCHEMBL9644012

SCHEMBL9644012

O=C(O)OCC1COC(=O)O1

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.38
MAPK1 P28482 1/20 0.38
ALDH1A1 P00352 1/20 0.33
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
MGLL Q99685 5/20 0.33
HTT P42858 1/20 0.32
RECQL P46063 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5607772 0.91 L3MBTL1 (0.35) L3MBTL1MAPK1ALDH1A1TP53CYP3A4
SCHEMBL9644015 0.87 L3MBTL1 (0.38) L3MBTL1MAPK1ALDH1A1TP53CYP3A4
SCHEMBL5836615 0.84 L3MBTL1 (0.37) L3MBTL1MAPK1ALDH1A1TP53CYP3A4
SCHEMBL21301194 0.84 LMNA (0.44) L3MBTL1ALDH1A1MGLL
SCHEMBL14783541 0.84 L3MBTL1 (0.37) L3MBTL1MAPK1ALDH1A1TP53CYP3A4
SCHEMBL16901532 0.84 L3MBTL1 (0.37) L3MBTL1MAPK1ALDH1A1TP53CYP3A4
SCHEMBL1323996 0.84 NLRP3 (0.41) L3MBTL1MAPK1ALDH1A1TP53CYP3A4
SCHEMBL18131857 0.82 MGLL (0.40) L3MBTL1MAPK1ALDH1A1TP53CYP3A4
SCHEMBL14003899 0.82 LMNA (0.46) MGLL
SCHEMBL18131859 0.82 MGLL (0.40) L3MBTL1MAPK1ALDH1A1TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024150897-A1 FOAMING AGENT COMPOSITION FOR POLYURETHANE AND METHOD OF PREPARING POLYURETHANE FOAM USING SAME 주식회사 세호 2024-07-18 WO claimed
US-20170022164-A1 QUINOLONE-3-DIARYLETHERS UNIV OREGON HEALTH & SCIENCE (US) 2017-01-26 US claimed
WO-2017015360-A1 QUINOLONE-3-DIARYLETHERS OREGON HEALTH & SCIENCE UNIVERSITY (US) 2017-01-26 WO claimed
US-4584408-A Preparation of 1,3-bis(aryloxy)-2-propanols THE DOW CHEMICAL COMPANY (US) 1986-04-22 US claimed
WO-2024150897-A1 FOAMING AGENT COMPOSITION FOR POLYURETHANE AND METHOD OF PREPARING POLYURETHANE FOAM USING SAME 주식회사 세호 2024-07-18 WO disclosed
CN-118344641-A Blowing agent composition for polyurethane and method for preparing polyurethane foam using the same 世好 2024-07-16 CN disclosed
CN-115023455-A Foamed polyurethane composition 美国主席团有限公司 2022-09-06 CN disclosed
EP-3950855-A1 NON-ISOCYANATE POLYURETHANE INKS FOR 3D PRINTING 3D Systems, Incorporated (US) 2022-02-09 EP disclosed
US-20200157053-A1 Method of Treating or Inhibiting Malaria UNIV OREGON HEALTH & SCIENCE (US) 2020-05-21 US disclosed
US-10584098-B2 Quinolone-3-diarylethers OREGON HEALTH & SCIENCE UNIVERSITY (US) 2020-03-10 US disclosed
US-20180362465-A1 QUINOLONE-3-DIARYLETHERS UNIV OREGON HEALTH & SCIENCE (US) 2018-12-20 US disclosed
EP-3066088-B1 CYCLIC CARBONATE AZIDE AKZO NOBEL CHEMICALS INT BV (NL) 2017-12-06 EP disclosed
US-9562114-B2 Cyclic carbonate azide AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2017-02-07 US disclosed
US-20170022164-A1 QUINOLONE-3-DIARYLETHERS UNIV OREGON HEALTH & SCIENCE (US) 2017-01-26 US disclosed
WO-2017015360-A1 QUINOLONE-3-DIARYLETHERS OREGON HEALTH & SCIENCE UNIVERSITY (US) 2017-01-26 WO disclosed
US-20160280805-A1 Cyclic Carbonate Azide WILMINGTON TRUST (LONDON) LIMITED, AS COLLATERAL AGENT (GB) 2016-09-29 US disclosed
US-5091543-A Reacting 1,2- or 1,3-diol with acrylic diester of carbonic acid ARCO CHEMICAL TECHNOLOGY, INC. (US) 1992-02-25 US disclosed
US-4584408-A Preparation of 1,3-bis(aryloxy)-2-propanols THE DOW CHEMICAL COMPANY (US) 1986-04-22 US disclosed
US-4584408-A Preparation of 1,3-bis(aryloxy)-2-propanols THE DOW CHEMICAL COMPANY (US) 1986-04-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180362465-A1 QUINOLONE-3-DIARYLETHERS RECQL, ELANE, ELF3 L3MBTL1 2274/4885MAPK1 4574/4885ALDH1A1 2150/4885
US-20170022164-A1 QUINOLONE-3-DIARYLETHERS RECQL, ELANE, ELF3 L3MBTL1 2274/4885MAPK1 4574/4885ALDH1A1 2150/4885
US-10584098-B2 Quinolone-3-diarylethers RECQL, ELANE, ELF3 L3MBTL1 2274/4885MAPK1 4574/4885ALDH1A1 2150/4885
US-20160280805-A1 Cyclic Carbonate Azide ATXN2L, ATXN10, CYCS L3MBTL1 2579/4885MAPK1 770/4885ALDH1A1 3084/4885
US-20200157053-A1 Method of Treating or Inhibiting Malaria ELANE, ELF3, ELOB L3MBTL1 1287/4885MAPK1 4570/4885ALDH1A1 2432/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.