SCHEMBL9507900

SCHEMBL9507900

O=C(O)c1cc(=O)n(-c2ccc(Cl)c(Cl)c2)[nH]1

nearest known ligand 0.72

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALKBH5 Q6P6C2 16/20 0.72
MME P08473 1/20 0.46
ALDH1A1 P00352 2/20 0.44
KMT2A Q03164 2/20 0.44
KDM4E B2RXH2 1/20 0.44
MAPT P10636 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
MEN1 O00255 1/20 0.44
GAA P10253 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
NOTUM Q6P988 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9505312 0.84 ALKBH5 (1.00) ALKBH5MMEALDH1A1KMT2AKDM4E
SCHEMBL11300860 0.81 ALKBH5 (0.72) ALKBH5MMEALDH1A1KMT2AKDM4E
SCHEMBL11420145 0.79 ALDH1A1 (0.61) ALKBH5ALDH1A1KMT2AKDM4EMAPT
SCHEMBL951472 0.78 ALKBH5 (0.73) ALKBH5ALDH1A1MAPTL3MBTL1
SCHEMBL9507906 0.78 ALKBH5 (0.44) ALKBH5MMEALDH1A1KMT2AKDM4E
SCHEMBL10956802 0.78 ALKBH5 (0.58) ALKBH5MMEALDH1A1KDM4EMAPT
SCHEMBL10787351 0.78 ALKBH5 (0.71) ALKBH5ALDH1A1KMT2AKDM4EMAPT
SCHEMBL11774629 0.78 ALKBH5 (0.71) ALKBH5ALDH1A1KMT2AKDM4EMAPT
SCHEMBL9505990 0.77 ALKBH5 (0.66) ALKBH5MMEALDH1A1KDM4EMAPT
SCHEMBL11314487 0.76 ALKBH5 (0.60) ALKBH5NOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0297397-B1 PREPARATION OF DIAZO AND AZO COMPOUNDS BAYER AG (DE) 1993-08-04 EP disclosed
US-4942225-A Preparation of diazo and azo compounds using azidoformamidium salts BAYER AKTIENGESELLSCHAFT (DE) 1990-07-17 US disclosed
EP-0093306-B1 METHODS FOR THE PREPARATION OF AZO COMPOUNDS, AND AZO COMPOUNDS BAYER AG (DE) 1986-09-24 EP disclosed
EP-0093306-A1 Methods for the preparation of azo compounds, and azo compounds BAYER AG (DE) 1983-11-09 EP disclosed