SCHEMBL9508137

SCHEMBL9508137

O=S(=O)(O)c1ccc2c(c1)Sc1ccc(S(=O)(=O)O)cc1S2

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.45
HSD17B10 Q99714 4/20 0.45
LMNA P02545 2/20 0.44
TSHR P16473 3/20 0.43
NT5E P21589 2/20 0.43
TDP1 Q9NUW8 3/20 0.42
KDM4E B2RXH2 2/20 0.41
HPGD P15428 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CASP6 P55212 2/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA7 P43166 1/20 0.40
CA14 Q9ULX7 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
SNCA P37840 2/20 0.38
POLB P06746 1/20 0.36
CYP2D6 P10635 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7360175 0.94 TSHR (0.46) ALDH1A1HSD17B10LMNATSHRNT5E
SCHEMBL9511439 0.77 ALDH1A1 (0.41) ALDH1A1HSD17B10TDP1
SCHEMBL9507650 0.77 ALDH1A1 (0.41) ALDH1A1HSD17B10TDP1
SCHEMBL28935010 0.74 LMNA (0.72) ALDH1A1HSD17B10LMNATSHRNT5E
SCHEMBL1538013 0.74 LMNA (0.72) ALDH1A1HSD17B10LMNATSHRNT5E
SCHEMBL5505299 0.74 TSHR (0.39) ALDH1A1HSD17B10LMNATSHRNT5E
SCHEMBL1416021 0.73 SNCA (0.60) ALDH1A1HSD17B10LMNATSHRNT5E
SCHEMBL3824024 0.73 SNCA (0.60) ALDH1A1HSD17B10LMNATSHRNT5E
SCHEMBL7357401 0.72 TDP1 (0.46) ALDH1A1HSD17B10LMNATDP1HPGD
SCHEMBL3825262 0.71 ALDH1A1 (0.57) ALDH1A1HSD17B10LMNATSHRNT5E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0399293-B1 PROCESS FOR PREPARING 2-CHLORO-4-NITRO-ALKYLBENZENE BAYER AG (DE) 1993-09-01 EP disclosed
EP-0399293-A1 Process for preparing 2-chloro-4-nitro-alkylbenzene BAYER AG (DE) 1990-11-28 EP disclosed