Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9508692 | 0.89 | LMNA (0.52) | FAAHCNR1CNR2ALDH1A1LMNA | |
| SCHEMBL9507403 | 0.87 | LMNA (0.59) | FAAHCNR1CNR2ALDH1A1LMNA | |
| SCHEMBL9511121 | 0.85 | LMNA (0.62) | FAAHCNR1CNR2ALDH1A1LMNA | |
| SCHEMBL9511067 | 0.85 | LMNA (0.62) | FAAHCNR1CNR2ALDH1A1LMNA | |
| SCHEMBL9509822 | 0.85 | LMNA (0.62) | FAAHCNR1CNR2ALDH1A1LMNA | |
| SCHEMBL9447620 | 0.85 | ALDH1A1 (0.48) | FAAHCNR1CNR2ALDH1A1LMNA | |
| SCHEMBL3099673 | 0.85 | ALDH1A1 (0.48) | FAAHCNR1CNR2ALDH1A1LMNA | |
| SCHEMBL9507681 | 0.83 | FAAH (0.42) | FAAHCNR1CNR2ALDH1A1LMNA | |
| SCHEMBL9511204 | 0.82 | CYP1A2 (0.47) | FAAHCNR1CNR2ALDH1A1LMNA | |
| SCHEMBL22127590 | 0.82 | ALDH1A1 (0.44) | FAAHCNR1CNR2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388960-B1 | OPTICALLY ACTIVE COMPOUNDS AND THEIR PREPARATION AND USE | HITACHI, LTD. (JP) | 1993-10-06 | — | — | EP | disclosed |
| US-5152919-A | Stability, chemical resistance, high speed response, large spo ntaneous polarization, molecular orientation and wide temperat ure range | HITACHI, LTD. (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0388960-A1 | Optically active compounds and their preparation and use | HITACHI, LTD. (JP) | 1990-09-26 | — | — | EP | disclosed |