Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tromethamine SCHEMBL7347818 | 0.86 | LMNA (0.62) | MEN1LMNAKMT2AFFAR3LCK | |
| Tromethamine SCHEMBL194002 | 0.86 | LMNA (0.62) | MEN1LMNAKMT2AFFAR3LCK | |
| Tromethamine SCHEMBL4581519 | 0.86 | LMNA (0.62) | MEN1LMNAKMT2AFFAR3LCK | |
| Tromethamine SCHEMBL3473649 | 0.84 | LMNA (0.53) | MEN1LMNAKMT2AFFAR3LCK | |
| SCHEMBL123823 | 0.83 | — | — | |
| Tromethamine SCHEMBL29111702 | 0.82 | LMNA (0.50) | MEN1LMNAKMT2AFFAR3LCK | |
| Tromethamine SCHEMBL5891164 | 0.79 | MEN1 (0.53) | MEN1LMNAKMT2AFFAR3LCK | |
| Acetic Acid SCHEMBL11592260 | 0.79 | MEN1 (0.45) | MEN1LMNAKMT2AFFAR3LCK | |
| Acetic Acid SCHEMBL28232411 | 0.79 | MEN1 (0.45) | MEN1LMNAKMT2AFFAR3LCK | |
| Acetic Acid SCHEMBL324547 | 0.79 | FFAR3 (0.37) | MEN1KMT2AFFAR3LCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0384180-B1 | FORMALDEHYDE-FREE ELECTROLESS COPPER PLATING SOLUTIONS | LeaRonal, Inc. (US) | 1993-08-11 | — | — | EP | claimed |
| EP-0467199-A2 | Preparation of printed circuit boards by metallization | LeaRonal, Inc. (US) | 1992-01-22 | — | — | EP | claimed |
| EP-0384180-A1 | Formaldehyde-free electroless copper plating solutions | LeaRonal, Inc. (US) | 1990-08-29 | — | — | EP | claimed |
| US-4877450-A | Formaldehyde-free electroless copper plating solutions | LEARONAL, INC. (US) | 1989-10-31 | — | — | US | claimed |
| EP-0384180-B1 | FORMALDEHYDE-FREE ELECTROLESS COPPER PLATING SOLUTIONS | LeaRonal, Inc. (US) | 1993-08-11 | — | — | EP | disclosed |
| EP-0467199-A2 | Preparation of printed circuit boards by metallization | LeaRonal, Inc. (US) | 1992-01-22 | — | — | EP | disclosed |
| EP-0384180-A1 | Formaldehyde-free electroless copper plating solutions | LeaRonal, Inc. (US) | 1990-08-29 | — | — | EP | disclosed |
| US-4877450-A | Formaldehyde-free electroless copper plating solutions | LEARONAL, INC. (US) | 1989-10-31 | — | — | US | disclosed |