SCHEMBL9510046

SCHEMBL9510046

Clc1cc2c(cc1Cl)Sc1cc(Oc3ccccc3)c(Cl)cc1S2

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
DPP4 P27487 1/20 0.42
LTA4H P09960 1/20 0.39
TSHR P16473 1/20 0.39
F2 P00734 1/20 0.38
F10 P00742 1/20 0.38
PNLIP P16233 1/20 0.38
MPO P05164 1/20 0.37
TPO P07202 1/20 0.37
EPX P11678 1/20 0.37
LPO P22079 1/20 0.37
MRGPRX4 Q96LA9 1/20 0.36
ALDH1A1 P00352 1/20 0.36
ALOX12 P18054 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
GPR55 Q9Y2T6 1/20 0.36
P2RY1 P47900 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10937945 0.82 CYP1A2 (0.53) CYP1A2CYP3A4CYP2C9CYP2C19DPP4
SCHEMBL9699717 0.80 CYP1A2 (0.41) CYP1A2CYP3A4CYP2C9CYP2C19DPP4
SCHEMBL11819263 0.73 CYP1A2 (0.59) CYP1A2CYP3A4CYP2C9CYP2C19DPP4
SCHEMBL9617591 0.72 PNLIP (0.51) CYP1A2CYP3A4CYP2C9CYP2C19DPP4
SCHEMBL5377407 0.72 L3MBTL1 (0.45) CYP1A2CYP3A4CYP2C9CYP2C19DPP4
SCHEMBL10943177 0.72 CYP1A2 (0.58) CYP1A2CYP3A4CYP2C9CYP2C19DPP4
SCHEMBL11196187 0.71 CYP1A2 (0.52) CYP1A2CYP3A4CYP2C9CYP2C19DPP4
SCHEMBL3793518 0.71 LTA4H (0.50) CYP1A2CYP3A4CYP2C9CYP2C19DPP4
SCHEMBL3783924 0.71 CYP1A2 (0.52) CYP1A2CYP3A4CYP2C9CYP2C19DPP4
SCHEMBL2087304 0.71 CYP1A2 (0.67) CYP1A2CYP3A4CYP2C9CYP2C19PNLIP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0399293-B1 PROCESS FOR PREPARING 2-CHLORO-4-NITRO-ALKYLBENZENE BAYER AG (DE) 1993-09-01 EP disclosed
EP-0399293-A1 Process for preparing 2-chloro-4-nitro-alkylbenzene BAYER AG (DE) 1990-11-28 EP disclosed