Methylene Chloride

Methylene Chloride

SCHEMBL951080

CCN(C(C)C)C(C)C.CO.ClCCl

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylene Chloride SCHEMBL2683607 0.94 MEN1 (0.50) MEN1KMT2AALDH1A1TSHR
Methyl Alcohol SCHEMBL2652388 0.91 MEN1 (0.38) MEN1KMT2ATSHR
1,2-Dichloroethane SCHEMBL25301300 0.85 MEN1 (0.55) MEN1KMT2AALDH1A1TSHR
SCHEMBL1746 0.84
SCHEMBL5544690 0.84 MEN1 (0.42) MEN1KMT2A
SCHEMBL7097725 0.84
Chlorolithium SCHEMBL27996451 0.81 MEN1 (0.43) MEN1KMT2A
SCHEMBL6063151 0.81 MEN1 (0.43) MEN1KMT2AALDH1A1TSHR
SCHEMBL4912357 0.81 MEN1 (0.43) MEN1KMT2A
Isopropyl Alcohol SCHEMBL28105402 0.81 ALDH1A1 (0.40) MEN1KMT2AALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240199745-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES ABBVIE INC (US) 2024-06-20 US disclosed
WO-2024043250-A1 CYCLIC PEPTIDE OR SALT THEREOF, AND MDMX INHIBITOR 富士フイルム株式会社 2024-02-29 WO disclosed
WO-2024043249-A1 CYCLIC PEPTIDE OR SALT THEREOF AND MDMX INHIBITOR 富士フイルム株式会社 2024-02-29 WO disclosed
EP-3888689-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES AbbVie Inc. (US) 2021-10-06 EP disclosed
US-10947289-B2 Glyco-modified atrial natriuretic peptide DAIICHI SANKYO COMPANY, LIMITED (JP) 2021-03-16 US disclosed
US-20210040170-A1 GLYCO-MODIFIED ATRIAL NATRIURETIC PEPTIDE DAIICHI SANKYO COMPANY, LIMITED (JP) 2021-02-11 US disclosed
EP-3735990-A1 ANTIBODY DRUG CONJUGATES WITH CELL PERMEABLE BCL-XL INHIBITORS Abbvie Inc. (US) 2020-11-11 EP disclosed
US-20200246323-A1 Antibody Drug Conjugates with Cell Permeable BCL-XL Inhibitors ABBVIE INC. (US) 2020-08-06 US disclosed
EP-3229844-B1 ANTIBODY DRUG CONJUGATES WITH CELL PERMEABLE BCL-XL INHIBITORS ABBVIE INC (US) 2020-03-04 EP disclosed
US-20190153107-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES ABBVIE INC. (US) 2019-05-23 US disclosed
EP-1183229-A1 GLUCAGON ANTAGONISTS/INVERSE AGONISTS NOVO NORDISK A/S (DK) 2002-03-06 EP disclosed
WO-2000069810-A1 GLUCAGON ANTAGONISTS/INVERSE AGONISTS NOVO NORDISK A/S (DK) 2000-11-23 WO disclosed
US-6127359-A Bicyclic fibrinogen antagonists SMITHKLINE BEECHAM CORPORATION (US) 2000-10-03 US disclosed
US-5939412-A Bicyclic fibrinogen antagonists SMITHKLINE BEECHAM CORPORATION (US) 1999-08-17 US disclosed
US-5693636-A Bicyclic fibrinogen antagonists SMITHKLINE BEECHAM CORPORATION (US) 1997-12-02 US disclosed
EP-0495265-B1 Acid-labile linker molecules AKZO NOBEL NV (NL) 1994-08-03 EP disclosed
EP-0593603-A1 BICYCLIC FIBRINOGEN ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1994-04-27 EP disclosed
US-5306809-A Cancer immune therapy AKZO N.V. (NL) 1994-04-26 US disclosed
WO-1993000095-A2 BICYCLIC FIBRINOGEN ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1993-01-07 WO disclosed
EP-0495265-A1 Acid-labile linker molecules Akzo Nobel N.V. (NL) 1992-07-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10947289-B2 Glyco-modified atrial natriuretic peptide NPPA, NPR1, NPR3 MEN1 1110/4885KMT2A 3687/4885ALDH1A1 2820/4885
US-20240199745-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES EGFR, ERBB2, ERBB3 MEN1 3881/4885KMT2A 1606/4885ALDH1A1 1891/4885
US-20190153107-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES EGFR, ERBB2, ERBB3 MEN1 3881/4885KMT2A 1606/4885ALDH1A1 1891/4885
US-20210040170-A1 GLYCO-MODIFIED ATRIAL NATRIURETIC PEPTIDE NPPA, NPR1, NPR3 MEN1 1110/4885KMT2A 3687/4885ALDH1A1 2820/4885
US-20200246323-A1 Antibody Drug Conjugates with Cell Permeable BCL-XL Inhibitors BCL2, BCL2L10, BAX MEN1 4371/4885KMT2A 2285/4885ALDH1A1 2251/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.