Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | MMP3 | P08254 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.55 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 4/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9511113 | 0.82 | MMP1 (0.47) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL9508041 | 0.82 | GABRR1 (0.45) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL14763891 | 0.79 | MMP1 (0.48) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL9511204 | 0.78 | CYP1A2 (0.47) | GABRR1CYP1A2BLMFAAHCNR1 | |
| SCHEMBL9509846 | 0.77 | TSHR (0.48) | GABRR1CYP1A2BLMFAAHACE2 | |
| SCHEMBL13576868 | 0.77 | MMP1 (0.55) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL31426915 | 0.76 | FAAH (0.51) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL9509874 | 0.76 | LMNA (0.50) | GABRR1CYP1A2BLMFAAHCNR1 | |
| SCHEMBL22127608 | 0.75 | GABRR1 (0.46) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL9511255 | 0.75 | GABRR1 (0.46) | GABRR1CYP1A2BLMFAAHCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388960-B1 | OPTICALLY ACTIVE COMPOUNDS AND THEIR PREPARATION AND USE | HITACHI, LTD. (JP) | 1993-10-06 | — | — | EP | disclosed |
| US-5152919-A | Stability, chemical resistance, high speed response, large spo ntaneous polarization, molecular orientation and wide temperat ure range | HITACHI, LTD. (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0388960-A1 | Optically active compounds and their preparation and use | HITACHI, LTD. (JP) | 1990-09-26 | — | — | EP | disclosed |