SCHEMBL9511270

SCHEMBL9511270

CS(=O)(=O)c1cc2c(cc1Cl)Sc1cc(S(C)(=O)=O)c(Cl)cc1S2

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.35
ALDH1A1 P00352 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA3 P07451 1/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CA14 Q9ULX7 1/20 0.32
CA5B Q9Y2D0 1/20 0.32
PIK3CD O00329 1/20 0.32
PIK3CA P42336 1/20 0.32
PIK3CB P42338 1/20 0.32
PIK3CG P48736 1/20 0.32
GRM4 Q14833 1/20 0.32
CCR2 P41597 2/20 0.32
GLP1R P43220 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9510093 0.80 TRPV4 (0.41) CA12CA1CA2CA3CA4
SCHEMBL9507595 0.80 TRPV4 (0.41) CA12CA1CA2CA3CA4
SCHEMBL9510017 0.78 CTPS1 (0.33) ALDH1A1
SCHEMBL15461575 0.77 L3MBTL1 (0.48) L3MBTL1ALDH1A1CA12CA1CA2
SCHEMBL8056461 0.73 L3MBTL1 (0.47) L3MBTL1ALDH1A1CA12CA1CA2
SCHEMBL9507618 0.72 GAA (0.48) L3MBTL1ALDH1A1CA2HSD11B1
SCHEMBL2654515 0.71 PTGS2 (0.42) L3MBTL1CCR2
SCHEMBL11328574 0.70 GAA (0.52) L3MBTL1ALDH1A1CA12CA1CA2
SCHEMBL2930389 0.70 HPGD (0.48) L3MBTL1ALDH1A1CA12CA1CA2
SCHEMBL9510026 0.69 AHR (0.39) ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0399293-B1 PROCESS FOR PREPARING 2-CHLORO-4-NITRO-ALKYLBENZENE BAYER AG (DE) 1993-09-01 EP disclosed
US-5095157-A Friedel-crafts catalyst BAYER AKTIENGESELLSCHAFT (DE) 1992-03-10 US disclosed
EP-0399293-A1 Process for preparing 2-chloro-4-nitro-alkylbenzene BAYER AG (DE) 1990-11-28 EP disclosed