Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 6/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9456708 | 0.79 | CYP1A2 (0.61) | CYP1A2CYP2C9CYP2C19ADORA3MEN1 | |
| SCHEMBL10438827 | 0.78 | ALDH1A1 (0.38) | ALOX5ADORA3KMT2AALDH1A1GABRA2 | |
| SCHEMBL9571758 | 0.74 | NPC1 (0.46) | CYP1A2CYP2C9CYP2C19ALOX5ADORA3 | |
| SCHEMBL9511701 | 0.74 | ALOX5 (0.45) | CYP1A2CYP2C9CYP2C19ALOX5ADORA3 | |
| SCHEMBL9571764 | 0.73 | RAB9A (0.68) | CYP1A2CYP2C9CYP2C19SMN1; SMN2ALDH1A1 | |
| SCHEMBL10970985 | 0.70 | ALOX5 (0.53) | CYP1A2CYP2C9CYP2C19ALOX5ADORA3 | |
| SCHEMBL9571754 | 0.70 | NPC1 (0.52) | CYP1A2CYP2C9CYP2C19ALOX5MEN1 | |
| SCHEMBL7095207 | 0.70 | CUL4A (0.46) | CYP1A2CYP2C9CYP2C19ALOX5MEN1 | |
| SCHEMBL1030204 | 0.69 | ALOX5 (0.43) | CYP1A2CYP2C9CYP2C19ALOX5MEN1 | |
| SCHEMBL9268884 | 0.69 | TSHR (0.47) | ALOX5MEN1KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0380985-B1 | Esters of 4-aryl-2-halogen imidazol-5-carbonic acid, their preparation and use | BASF AG (DE) | 1993-12-08 | — | — | EP | disclosed |
| EP-0380985-A2 | Esters of 4-aryl-2-halogen imidazol-5-carbonic acid, their preparation and use | BASF Aktiengesellschaft (DE) | 1990-08-08 | — | — | EP | disclosed |