SCHEMBL7095207

SCHEMBL7095207

CCOC(=O)Oc1c(Cl)cc(-c2ccccc2)cc1Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CUL4A Q13619 1/20 0.46
RAB9A P51151 4/20 0.45
CYP1A2 P05177 3/20 0.45
ALOX5 P09917 1/20 0.43
AKR1C2 P52895 1/20 0.43
AKR1C1 Q04828 1/20 0.43
ALDH1A1 P00352 4/20 0.42
HPGD P15428 4/20 0.42
KDM4E B2RXH2 3/20 0.42
CYP2C19 P33261 2/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
GRM6 O15303 1/20 0.42
PDK2 Q15119 1/20 0.41
PPARA Q07869 1/20 0.40
DHODH Q02127 1/20 0.40
NPC1 O15118 3/20 0.40
XBP1 P17861 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7571353 0.82 CYP1A2 (0.46) CUL4ARAB9ACYP1A2ALOX5ALDH1A1
SCHEMBL19543205 0.80 CUL4A (0.52) CUL4AALDH1A1HPGDKDM4EMAPT
SCHEMBL17697666 0.76 LMNA (0.47) RAB9ACYP1A2ALOX5ALDH1A1HPGD
SCHEMBL6976915 0.76 NPC1 (0.51) RAB9ACYP1A2ALOX5ALDH1A1HPGD
SCHEMBL11856382 0.73 CYP1A2 (0.46) CUL4ARAB9ACYP1A2ALDH1A1HPGD
SCHEMBL19583350 0.73 TSHR (0.48) ALDH1A1HPGDKDM4EMAPTLMNA
SCHEMBL30004235 0.73 TSHR (0.48) ALDH1A1HPGDKDM4EMAPTLMNA
SCHEMBL7571401 0.73 PPARG (0.52) ALOX5ALDH1A1HPGDPPARADHODH
SCHEMBL5059050 0.73 TSHR (0.54) RAB9ACYP1A2ALDH1A1HPGDKDM4E
SCHEMBL5706075 0.72 MAPT (0.47) CUL4ARAB9AALDH1A1NPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0970059-B1 DISUBSTITUTED BIPHENYLOXAZOLINES BAYER CROPSCIENCE AG (DE) 2003-08-20 EP disclosed
US-20020086892-A1 For controlling animal pests, in particular: insects, arachnids and nematodes BAYER AKTIENGESELLSCHAFT (DE) 2002-07-04 US disclosed
US-6410581-B1 INSECTICIDES, MITICIDES, NEMATOCIDES BAYER AKTIENGESELLSCHAFT (DE) 2002-06-25 US disclosed
EP-0970059-A1 DISUBSTITUTED BIPHENYLOXAZOLINES BAYER AG (DE) 2000-01-12 EP disclosed
WO-1998039310-A1 DISUBSTITUTED BIPHENYLOXAZOLINES BAYER AKTIENGESELLSCHAFT (DE) 1998-09-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020086892-A1 For controlling animal pests, in particular: insects, arachnids and nematodes ATXN2, HAX1, ANTXR2 CUL4A 1482/4885RAB9A 1115/4885CYP1A2 89/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.