Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | P4HB | P07237 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9512238 | 1.00 | PPARG (0.42) | PPARGSNCAFBP1ALDH1A1LMNA | |
| SCHEMBL16746567 | 0.89 | CA2 (0.43) | PPARGALDH1A1MAPTKDM4EGAA | |
| SCHEMBL7718268 | 0.86 | APP (0.42) | PPARGALDH1A1LMNAMAPTL3MBTL1 | |
| SCHEMBL9915609 | 0.86 | APP (0.42) | PPARGALDH1A1LMNAMAPTL3MBTL1 | |
| SCHEMBL9915630 | 0.86 | APP (0.42) | PPARGALDH1A1LMNAMAPTL3MBTL1 | |
| SCHEMBL21594521 | 0.79 | ALDH1A1 (0.53) | FBP1ALDH1A1LMNAMAPTL3MBTL1 | |
| SCHEMBL21594513 | 0.79 | ALDH1A1 (0.53) | FBP1ALDH1A1LMNAMAPTL3MBTL1 | |
| SCHEMBL7466596 | 0.79 | MAPT (0.45) | ALDH1A1MAPTL3MBTL1KDM4EGAA | |
| SCHEMBL2604913 | 0.79 | RELA (0.52) | PPARGALDH1A1MAPTL3MBTL1MAOB | |
| SCHEMBL22244209 | 0.79 | CYP3A4 (0.38) | PPARGALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350112-B1 | POLYURETHANES PREPARED FROM NON-LINEAR OPTICAL ACTIVE DIOLS | Akzo Nobel N.V. (NL) | 1993-10-06 | — | — | EP | disclosed |
| US-5001209-A | Non-linear optical active diols and polyurethanes prepared therefrom | AKZO N.V. (NL) | 1991-03-19 | — | — | US | disclosed |
| EP-0350112-A1 | Polyurethanes prepared from non-linear optical active diols | Akzo Nobel N.V. (NL) | 1990-01-10 | — | — | EP | disclosed |