Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | S1PR1 | P21453 | 11/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9512132 | 0.84 | MMP2 (0.60) | ADAMTS5MMP2S1PR1L3MBTL1MEN1 | |
| SCHEMBL8895575 | 0.83 | NPSR1 (0.56) | ADAMTS5MMP2S1PR1L3MBTL1ALDH1A1 | |
| SCHEMBL9510545 | 0.83 | ALDH1A1 (0.51) | ADAMTS5MMP2S1PR1L3MBTL1ALDH1A1 | |
| SCHEMBL9512064 | 0.81 | ADRB2 (0.48) | ADAMTS5MMP2S1PR1L3MBTL1ALDH1A1 | |
| SCHEMBL1287456 | 0.81 | MEN1 (0.57) | ADAMTS5MMP2S1PR1L3MBTL1ALDH1A1 | |
| SCHEMBL15387943 | 0.81 | MEN1 (0.57) | ADAMTS5MMP2S1PR1L3MBTL1ALDH1A1 | |
| SCHEMBL1287324 | 0.81 | MEN1 (0.57) | ADAMTS5MMP2S1PR1L3MBTL1ALDH1A1 | |
| SCHEMBL8894761 | 0.80 | ADAMTS5 (0.53) | ADAMTS5MMP2S1PR1L3MBTL1ALDH1A1 | |
| SCHEMBL8895536 | 0.79 | ADAMTS5 (0.52) | ADAMTS5MMP2S1PR1L3MBTL1ALDH1A1 | |
| SCHEMBL8895463 | 0.79 | ADAMTS5 (0.51) | ADAMTS5MMP2S1PR1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0325245-B1 | Phenoxyacetic acid derivatives, preparation thereof, pharmaceutical compositions comprising them and use | TANABE SEIYAKU CO (JP) | 1993-10-20 | — | — | EP | disclosed |
| US-4948810-A | PLATELET AGGREGATION INHIBITORS | TANABE SEIYAKU CO., LTD. (JP) | 1990-08-14 | — | — | US | disclosed |