SCHEMBL9512822

SCHEMBL9512822

CCc1cccc(COc2ccc(C(=O)O)cc2)c1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 2/20 0.72
RXRB P28702 2/20 0.72
MRGPRX4 Q96LA9 7/20 0.69
SMN1; SMN2 Q16637 4/20 0.69
NR4A2 P43354 3/20 0.69
TP53 P04637 2/20 0.69
PKM P14618 2/20 0.69
NFKB1 P19838 2/20 0.69
NFKB2 Q00653 2/20 0.69
RELA Q04206 2/20 0.69
RXRG P48443 1/20 0.69
NR4A1 P22736 1/20 0.69
NR4A3 Q92570 1/20 0.69
PTPRC P08575 1/20 0.66
PTPN1 P18031 1/20 0.66
RAB9A P51151 2/20 0.65
RXFP1 Q9HBX9 1/20 0.65
SRD5A2 P31213 1/20 0.63
PLA2G4B P0C869 1/20 0.60
NPC1 O15118 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13951781 0.85 MAOB (0.78) RXRARXRBMRGPRX4SMN1; SMN2NR4A2
SCHEMBL8861229 0.84 RXRA (1.00) RXRARXRBSMN1; SMN2NR4A2NR4A1
SCHEMBL25555307 0.84 RXRA (1.00) RXRARXRBSMN1; SMN2NR4A2NR4A1
SCHEMBL3649253 0.84 MRGPRX4 (0.76) RXRARXRBMRGPRX4SMN1; SMN2NR4A2
SCHEMBL1123461 0.83 NR4A2 (0.81) RXRARXRBMRGPRX4SMN1; SMN2NR4A2
SCHEMBL3918360 0.82 LMNA (0.61) MRGPRX4SMN1; SMN2TP53PKMNFKB1
SCHEMBL3918721 0.82 MAOB (0.58) MRGPRX4SMN1; SMN2TP53PKMNFKB1
SCHEMBL4059143 0.82 NR4A2 (1.00) RXRARXRBSMN1; SMN2NR4A2PKM
SCHEMBL228477 0.82 NR4A2 (1.00) RXRARXRBSMN1; SMN2NR4A2PKM
SCHEMBL6830467 0.82 NR4A2 (1.00) RXRARXRBSMN1; SMN2NR4A2PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0379290-B1 Flux composition COOKSON GROUP PLC (GB) 1993-10-27 EP claimed
US-5041169-A Comprising phenyl benzoate, solvent and activating agent, soldering printed circuit boards COOKSON GROUP PLC (GB) 1991-08-20 US claimed
EP-0379290-A1 Flux composition COOKSON GROUP plc (GB) 1990-07-25 EP claimed
EP-0379290-B1 Flux composition COOKSON GROUP PLC (GB) 1993-10-27 EP disclosed
US-5041169-A Comprising phenyl benzoate, solvent and activating agent, soldering printed circuit boards COOKSON GROUP PLC (GB) 1991-08-20 US disclosed
EP-0379290-A1 Flux composition COOKSON GROUP plc (GB) 1990-07-25 EP disclosed