Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NQO1 | P15559 | 1/20 | 0.38 |
| ▸ | TPMT | P51580 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9094972 | 0.91 | LCK (0.46) | PKMCYP3A4ALOX15MEN1KMT2A | |
| SCHEMBL9329600 | 0.90 | CYP3A4 (0.40) | PKMCYP3A4ALOX15GSK3BMEN1 | |
| SCHEMBL9330285 | 0.88 | POLB (0.51) | CYP3A4ALOX15GSK3BMEN1KMT2A | |
| SCHEMBL9513890 | 0.86 | GSK3B (0.55) | PKMCYP3A4GSK3BMEN1KMT2A | |
| SCHEMBL9328253 | 0.86 | KDM4E (0.40) | PKMCYP3A4ALOX15POLBLCK | |
| SCHEMBL1368787 | 0.84 | CYP3A4 (0.51) | PKMCYP3A4ALOX15MEN1KMT2A | |
| SCHEMBL30209179 | 0.84 | CYP3A4 (0.51) | PKMCYP3A4ALOX15MEN1KMT2A | |
| SCHEMBL4299733 | 0.83 | PKM (0.60) | PKMCYP3A4POLBLCKFYN | |
| SCHEMBL9603034 | 0.83 | CYP3A4 (0.43) | PKMCYP3A4ALOX15MEN1KMT2A | |
| SCHEMBL9327972 | 0.83 | LMNA (0.42) | CYP3A4ALOX15GSK3BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62294677-A | — | — | None | — | — | JP | disclosed |
| EP-0267970-B1 | NOVEL BIPHENYL DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE | TSUMURA & CO (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-5264594-A | Alkylation of carbonates | TSUMURA & CO. (JP) | 1993-11-23 | — | — | US | disclosed |
| US-4996331-A | Novel biphenyl derivative and preparation and use thereof | TSUMURA & CO. (JP) | 1991-02-26 | — | — | US | disclosed |
| US-4925872-A | HEPATITIS | TSUMURA & CO. (JP) | 1990-05-15 | — | — | US | disclosed |
| US-4849448-A | LIVER DISORDER TREATMENT | TSUMURA JUNTENDO, INC. (JP) | 1989-07-18 | — | — | US | disclosed |
| EP-0267970-A1 | NOVEL BIPHENYL DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE | TSUMURA & CO. (JP) | 1988-05-25 | — | — | EP | disclosed |
| JP-S62294677-A | NOVEL BIPHENYL AND PRODUCTION THEREOF | TSUMURA JUNTENDO INC | 1987-12-22 | — | — | JP | disclosed |