Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | BCL2 | P10415 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5435016 | 0.86 | ALDH1A1 (0.48) | BCL2L1LMNACYP2D6TSHRALDH1A1 | |
| SCHEMBL6547955 | 0.86 | TSHR (0.42) | LMNACYP2D6TSHRALDH1A1TDP1 | |
| SCHEMBL10782398 | 0.85 | CALM1 (0.44) | CALM1HTR2ABCL2BCL2L1LMNA | |
| SCHEMBL9681510 | 0.84 | APP (0.38) | TSHRALDH1A1TDP1SLC6A2L3MBTL1 | |
| SCHEMBL6547271 | 0.84 | GABRA1 (0.41) | CALM1HTR2ABCL2BCL2L1LMNA | |
| SCHEMBL29470998 | 0.83 | BCL2 (0.45) | CALM1HTR2ABCL2BCL2L1LMNA | |
| SCHEMBL8322110 | 0.83 | HTR2A (0.47) | CALM1HTR2ABCL2BCL2L1LMNA | |
| SCHEMBL8815094 | 0.83 | BCL2 (0.45) | CALM1HTR2ABCL2BCL2L1LMNA | |
| SCHEMBL9514064 | 0.83 | CA2 (0.55) | BCL2BCL2L1TSHRALDH1A1TDP1 | |
| SCHEMBL10900432 | 0.82 | HTR2A (0.41) | CALM1HTR2ABCL2BCL2L1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5231104-A | Anticholinergic | PFIZER INC. (US) | 1993-07-27 | — | — | US | claimed |
| US-5089505-A | Anticholinergic agents | PFIZER INC. (US) | 1992-02-18 | — | — | US | claimed |
| US-20230286997-A1 | Compounds for the Treatment of Cancer and Inflammatory Disease | SHY Therapeutics LLC | 2023-09-14 | — | — | US | disclosed |
| US-11560390-B2 | Compounds for the treatment of cancer and inflammatory disease | SHY Therapeutics LLC (US) | 2023-01-24 | — | — | US | disclosed |
| EP-0717098-B1 | A refrigerating machine oil and a fluid composition for use in a refrigerating machine | NIPPON MITSUBISHI OIL CORP (JP) | 2004-01-21 | — | — | EP | disclosed |
| US-5817251-A | AROMATIC HYDROCARBON LUBRICANT | NIPPON OIL CO., LTD. (JP) | 1998-10-06 | — | — | US | disclosed |
| US-5711895-A | Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group | NIPPON OIL CO., LTD. (JP) | 1998-01-27 | — | — | US | disclosed |
| EP-0717098-A2 | A refrigerating machine oil and a fluid composition for use in a refrigerating machine | NIPPON OIL CO. LTD. (JP) | 1996-06-19 | — | — | EP | disclosed |
| EP-0229372-B1 | PRESSURE SENSITIVE COPYING MATERIAL | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1990-05-09 | — | — | EP | disclosed |
| US-4879269-A | DEVELOPERS, COUPLERS, COLORS | NIPPON PETROCHEMICALS CO., LTD. (JP) | 1989-11-07 | — | — | US | disclosed |
| EP-0229372-A1 | Pressure sensitive copying material | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1987-07-22 | — | — | EP | disclosed |
| US-4036860-A | OXIDATION OF A DIPHENYLMETHANE, VANADIUM-TITANIUM OXIDE CATALYST ON | BASF AKTIENGESELLSCHAFT (DT) | 1977-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11560390-B2 | Compounds for the treatment of cancer and inflammatory disease | MAPK6, MAP3K6, MAPK4 | CALM1 1492/4885HTR2A 4536/4885BCL2 792/4885 |
| US-20230286997-A1 | Compounds for the Treatment of Cancer and Inflammatory Disease | MAPK6, MAP3K6, MAPK4 | CALM1 1492/4885HTR2A 4536/4885BCL2 792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.