Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9515692 | 1.00 | ALDH1A1 (0.40) | ALDH1A1LMNAMAPTMAPK1ALOX15 | |
| SCHEMBL9514529 | 0.85 | MEN1 (0.33) | — | |
| SCHEMBL28387385 | 0.79 | ALDH1A1 (0.44) | ALDH1A1LMNAMAPTMAPK1ALOX15 | |
| SCHEMBL7287991 | 0.76 | ALDH1A1 (0.46) | ALDH1A1LMNAMAPTMAPK1ALOX15 | |
| SCHEMBL5038675 | 0.76 | TSHR (0.42) | MAPT | |
| SCHEMBL16907298 | 0.75 | ALDH1A1 (0.44) | ALDH1A1LMNAMAPTMAPK1ALOX15 | |
| SCHEMBL3487938 | 0.75 | ALDH1A1 (0.44) | ALDH1A1LMNAMAPTMAPK1ALOX15 | |
| SCHEMBL30366016 | 0.71 | LMNA (0.68) | ALDH1A1LMNAMAPTMAPK1ALOX15 | |
| SCHEMBL120124 | 0.71 | — | — | |
| SCHEMBL17431574 | 0.69 | CES2 (0.32) | CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0290878-B1 | Optically active compounds and process for producing thereof | CHISSO CORP (JP) | 1993-12-22 | — | — | EP | claimed |
| US-4882451-A | SILYL ALCOHOLS OR ESTERS | CHISSO CORPORATION (JP) | 1989-11-21 | — | — | US | claimed |
| EP-0290878-A2 | Optically active compounds and process for producing thereof | Chisso Corporation (JP) | 1988-11-17 | — | — | EP | claimed |
| EP-0290878-B1 | Optically active compounds and process for producing thereof | CHISSO CORP (JP) | 1993-12-22 | — | — | EP | disclosed |
| US-4882451-A | SILYL ALCOHOLS OR ESTERS | CHISSO CORPORATION (JP) | 1989-11-21 | — | — | US | disclosed |
| EP-0290878-A2 | Optically active compounds and process for producing thereof | Chisso Corporation (JP) | 1988-11-17 | — | — | EP | disclosed |