Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 13/20 | 0.52 |
| ▸ | CXCR1 | P25024 | 11/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566902 | 0.90 | CXCR2 (0.62) | CXCR2CXCR1NPC1RAB9AP4HTM | |
| SCHEMBL9519474 | 0.88 | CXCR2 (0.50) | CXCR2CXCR1MEN1MAPTKMT2A | |
| SCHEMBL9516951 | 0.88 | NPC1 (0.52) | CXCR2CXCR1MEN1MAPTKMT2A | |
| SCHEMBL9517015 | 0.85 | P4HTM (0.51) | CXCR2CXCR1MEN1MAPTKMT2A | |
| SCHEMBL9566811 | 0.85 | CXCR2 (0.57) | CXCR2CXCR1MEN1KMT2ANPC1 | |
| SCHEMBL9519589 | 0.83 | CXCR2 (0.54) | CXCR2CXCR1MEN1KMT2AP4HTM | |
| SCHEMBL9519137 | 0.78 | NPC1 (0.54) | MEN1MAPTKMT2ANPC1RAB9A | |
| SCHEMBL9566868 | 0.78 | CXCR2 (0.60) | CXCR2CXCR1NPC1RAB9AP4HTM | |
| SCHEMBL9566786 | 0.78 | CXCR2 (0.57) | CXCR2CXCR1NPC1RAB9AP4HTM | |
| SCHEMBL3950709 | 0.78 | BAZ2B (0.49) | MEN1MAPTKMT2AHTTP4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1079466-A | 4-or 5-(sulphur) acylimino-and (inferior sulphur) amidopyridine and pyridine-N-oxide thereof | HOECHST AG (DE) | 1993-12-15 | — | — | CN | disclosed |
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |