Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 12/20 | 0.50 |
| ▸ | CXCR1 | P25024 | 11/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.45 |
| ▸ | DDX3X | O00571 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566868 | 0.91 | CXCR2 (0.60) | CXCR2CXCR1P4HTMRAB9ANPC1 | |
| SCHEMBL9515480 | 0.88 | CXCR2 (0.52) | CXCR2CXCR1MEN1MAPTKMT2A | |
| SCHEMBL9516029 | 0.88 | NPC1 (0.50) | MEN1MAPTKMT2ACASP3SENP7 | |
| SCHEMBL9519137 | 0.88 | NPC1 (0.54) | MEN1MAPTKMT2AP4HTMRAB9A | |
| SCHEMBL9519589 | 0.86 | CXCR2 (0.54) | CXCR2CXCR1MEN1KMT2AP4HTM | |
| SCHEMBL9566753 | 0.85 | CXCR2 (0.54) | CXCR2CXCR1MEN1KMT2AP4HTM | |
| SCHEMBL9517015 | 0.83 | P4HTM (0.51) | CXCR2CXCR1MEN1MAPTKMT2A | |
| SCHEMBL9566740 | 0.80 | CXCR2 (0.54) | CXCR2CXCR1P4HTMALDH1A1SMN1; SMN2 | |
| SCHEMBL9566769 | 0.79 | KDM4E (0.57) | CXCR2CXCR1MEN1MAPTKMT2A | |
| SCHEMBL9566825 | 0.79 | P4HTM (0.66) | MEN1MAPTKMT2AP4HTMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |