Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | NPR3 | P17342 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 3/20 | 0.39 |
| ▸ | CCR4 | P51679 | 1/20 | 0.39 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9517931 | 0.82 | AR (0.46) | ARHPGDLMNAALDH1A1KDM4E | |
| SCHEMBL9516196 | 0.82 | GABRA5 (0.50) | HPGDALDH1A1KDM4EGAAMAPT | |
| SCHEMBL9518150 | 0.77 | MEN1 (0.47) | ARALDH1A1GAAMAPTMEN1 | |
| SCHEMBL8170006 | 0.73 | ALDH1A1 (0.46) | LMNAALDH1A1MAPTKMT2A | |
| SCHEMBL9517133 | 0.73 | GABRA5 (0.42) | HPGDLMNAGAASMN1; SMN2 | |
| SCHEMBL9516086 | 0.71 | GABRA5 (0.41) | HPGDLMNASMN1; SMN2HTTKMT2A | |
| SCHEMBL5293554 | 0.71 | HPGD (0.59) | ARHPGDLMNAALDH1A1KDM4E | |
| SCHEMBL8869019 | 0.71 | HPGD (0.44) | ARHPGDLMNAALDH1A1KDM4E | |
| SCHEMBL8869499 | 0.71 | AR (0.42) | ARHPGDLMNAALDH1A1KDM4E | |
| SCHEMBL8870309 | 0.71 | CA12 (0.42) | ARHPGDLMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |