Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | AR | P10275 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9515571 | 0.88 | HDAC1 (0.46) | MEN1KMT2AARMAPTHDAC1 | |
| SCHEMBL9517040 | 0.86 | MEN1 (0.48) | MEN1KMT2AARMAPTHDAC1 | |
| SCHEMBL9516058 | 0.84 | KMT2A (0.50) | MEN1KMT2AARMAPTTDP1 | |
| SCHEMBL9517085 | 0.81 | ALDH1A1 (0.43) | MEN1KMT2AARMAPTALDH1A1 | |
| SCHEMBL9517241 | 0.81 | P4HTM (0.61) | — | |
| SCHEMBL9517193 | 0.80 | AR (0.59) | MEN1KMT2AARMAPTTDP1 | |
| SCHEMBL9656277 | 0.77 | KMT2A (0.48) | MEN1KMT2AARMAPTHDAC1 | |
| SCHEMBL9515567 | 0.77 | AR (0.47) | MEN1KMT2AARMAPTALDH1A1 | |
| SCHEMBL9654495 | 0.76 | HDAC1 (0.52) | MEN1KMT2AHDAC1HDAC8HDAC4 | |
| SCHEMBL9657802 | 0.75 | HDAC1 (0.53) | MEN1KMT2AHDAC1HDAC8HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |