Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 3/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 2/20 | 0.34 |
| ▸ | MPI | P34949 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9515929 | 0.82 | TDP1 (0.45) | HTTNPSR1TDP1DAOTP53 | |
| SCHEMBL6812238 | 0.81 | DAO (0.39) | HTTNPSR1TDP1DAOMAOA | |
| SCHEMBL11617330 | 0.79 | MAOA (0.49) | HTTNPSR1MAOAMAOBHPGD | |
| SCHEMBL6815592 | 0.76 | PNMT (0.47) | HTTNPSR1TDP1DAOTP53 | |
| SCHEMBL9647414 | 0.76 | DAO (0.32) | DAOMAOAMAOBHAO1 | |
| SCHEMBL10410234 | 0.75 | CDK1 (0.45) | HTTNPSR1TDP1DAOHPGD | |
| SCHEMBL11630453 | 0.74 | ALDH1A1 (0.38) | TDP1MAOAMAOBHPGDTP53 | |
| SCHEMBL9040127 | 0.73 | TDP1 (0.40) | HTTNPSR1TDP1DAOTP53 | |
| SCHEMBL7531348 | 0.72 | KIF11 (0.42) | HTTNPSR1TDP1DAOMEN1 | |
| SCHEMBL15960057 | 0.72 | THRB (0.48) | HTTNPSR1TDP1DAOMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9889111-B2 | Pharmaceutical composition comprising omega-(arylsulfonyl)alkylnitrile | OLATEC THERAPEUTICS LLC (US) | 2018-02-13 | — | — | US | disclosed |
| US-20170105962-A1 | PHARMACEUTICAL COMPOSITION COMPRISING OMEGA-(ARYLSULFONYL)ALKYLNITRILE | OLATEC THERAPEUTICS, INC. | 2017-04-20 | — | — | US | disclosed |
| US-20170105962-A1 | PHARMACEUTICAL COMPOSITION COMPRISING OMEGA-(ARYLSULFONYL)ALKYLNITRILE | OLATEC THERAPEUTICS, INC. | 2017-04-20 | — | — | US | disclosed |
| US-9481644-B2 | Pharmaceutical composition comprising omega-(arylsulfonyl)alkylnitrile | OLATEC THERAPEUTICS LLC (US) | 2016-11-01 | — | — | US | disclosed |
| US-9481644-B2 | Pharmaceutical composition comprising omega-(arylsulfonyl)alkylnitrile | OLATEC THERAPEUTICS LLC (US) | 2016-11-01 | — | — | US | disclosed |
| US-20150087701-A1 | PHARMACEUTICAL COMPOSITION COMPRISING OMEGA-(ARYLSULFONYL)ALKYLNITRILE | OLATEC THERAPEUTICS, INC. | 2015-03-26 | — | — | US | disclosed |
| US-20150087701-A1 | PHARMACEUTICAL COMPOSITION COMPRISING OMEGA-(ARYLSULFONYL)ALKYLNITRILE | OLATEC THERAPEUTICS, INC. | 2015-03-26 | — | — | US | disclosed |
| US-4876247-A | ANTIINFLAMMATORY AGENTS | SANOFI (FR) | 1989-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150087701-A1 | PHARMACEUTICAL COMPOSITION COMPRISING OMEGA-(ARYLSULFONYL)ALKYLNITRILE | ALOX15B, FADS1, ALOX15 | HTT 704/4885NPSR1 491/4885TDP1 4195/4885 |
| US-20170105962-A1 | PHARMACEUTICAL COMPOSITION COMPRISING OMEGA-(ARYLSULFONYL)ALKYLNITRILE | ALOX15B, FADS1, ALOX15 | HTT 704/4885NPSR1 491/4885TDP1 4195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.