Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 4/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9517230 | 0.90 | HSD11B1 (0.39) | HSD11B1HIF1AEPAS1POLBTRPM8 | |
| SCHEMBL9517911 | 0.89 | CXCR1 (0.37) | HDAC3HDAC1HDAC2HDAC6P4HTM | |
| SCHEMBL9519398 | 0.89 | SCD (0.41) | SCN9AHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL9516093 | 0.88 | HSD11B1 (0.43) | HSD11B1HIF1AEPAS1SCN9ATRPM8 | |
| SCHEMBL9517939 | 0.87 | EGFR (0.40) | SCN9ASCN5AP4HTM | |
| SCHEMBL9515773 | 0.86 | HSD11B1 (0.43) | HSD11B1HIF1AEPAS1TRPM8HDAC3 | |
| SCHEMBL9515466 | 0.85 | SMN1; SMN2 (0.38) | GAA | |
| SCHEMBL9516010 | 0.83 | TRPM8 (0.38) | HIF1AEPAS1SCN9APOLBTRPM8 | |
| SCHEMBL9516994 | 0.83 | SCN9A (0.38) | SCN9ASCN5AHDAC6P4HTM | |
| SCHEMBL9516266 | 0.82 | GRM5 (0.38) | SCN9ASCN5AKCNH2HDAC6P4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |