Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.37 |
| ▸ | MTTP | P55157 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9517170 | 0.91 | HDAC1 (0.39) | P4HTMBCL2L1MCL1PPARGHDAC3 | |
| SCHEMBL9516012 | 0.88 | HSD11B1 (0.39) | HSD11B1P4HTMTRPM8SCN9AKCNH2 | |
| SCHEMBL9515738 | 0.88 | P4HTM (0.43) | P4HTMBCL2L1MCL1SCN9ASCN5A | |
| SCHEMBL9517230 | 0.85 | HSD11B1 (0.39) | HSD11B1P4HTMTRPM8HIF1AEPAS1 | |
| SCHEMBL9515773 | 0.84 | HSD11B1 (0.43) | HSD11B1P4HTMTRPM8HIF1AEPAS1 | |
| SCHEMBL9519638 | 0.84 | BCL2L1 (0.42) | P4HTMBCL2L1MCL1HDAC1HDAC6 | |
| SCHEMBL9516087 | 0.83 | BCL2L1 (0.38) | P4HTMBCL2L1MCL1TRPM8SCN9A | |
| SCHEMBL9519398 | 0.80 | SCD (0.41) | SCN9AHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL9517911 | 0.78 | CXCR1 (0.37) | P4HTMHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL9517093 | 0.77 | P4HTM (0.39) | P4HTMBCL2L1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |