Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.37 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9515611 | 0.88 | EPHX2 (0.39) | P4HTMCXCR2CXCR1EPHX2CYP2C9 | |
| SCHEMBL9517911 | 0.83 | CXCR1 (0.37) | P4HTMKMT2ACXCR2CXCR1EPHX2 | |
| SCHEMBL9518022 | 0.83 | HDAC6 (0.39) | P4HTMKMT2ACXCR2CXCR1EPHX2 | |
| SCHEMBL9517088 | 0.82 | CXCR2 (0.38) | P4HTMKMT2ACXCR2CXCR1EPHX2 | |
| SCHEMBL9519649 | 0.79 | GRM5 (0.38) | P4HTMCXCR2CXCR1 | |
| SCHEMBL9517233 | 0.79 | POLB (0.38) | P4HTMADRB2ADRB1ADRB3MAPT | |
| SCHEMBL9517265 | 0.79 | EGFR (0.41) | P4HTM | |
| SCHEMBL9517230 | 0.78 | HSD11B1 (0.39) | P4HTMEPHX2GAA | |
| SCHEMBL9515738 | 0.77 | P4HTM (0.43) | P4HTMKMT2ACXCR2BCL2L1MCL1 | |
| SCHEMBL9517975 | 0.77 | P4HTM (0.53) | P4HTMKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |