⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9751877 | 0.64 | — | — | |
| SCHEMBL19820369 | 0.58 | — | — | |
| SCHEMBL7296773 | 0.57 | — | — | |
| SCHEMBL11873235 | 0.56 | — | — | |
| SCHEMBL7901999 | 0.55 | — | — | |
| SCHEMBL5010980 | 0.54 | GABRA1 (0.54) | — | |
| SCHEMBL5831274 | 0.53 | ALDH1A1 (0.33) | — | |
| SCHEMBL3856071 | 0.53 | NPSR1 (0.30) | — | |
| SCHEMBL456737 | 0.53 | ALDH1A1 (0.33) | — | |
| SCHEMBL11119104 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0346943-B1 | DIPHENYL-METHANE DERIVATIVE, PHARMACEUTICAL COMPOSITION AND USE | Eisai Co., Ltd. (JP) | 1993-02-17 | — | — | EP | claimed |
| US-5064848-A | Anticoagulants | EISAI CO., LTD. (JP) | 1991-11-12 | — | — | US | claimed |
| US-5206403-A | Diphenylethylene derivatives, pharmaceutical compositions containing same and treatment methods | EISAI CO., LTD. (JP) | 1993-04-27 | — | — | US | disclosed |
| EP-0346943-B1 | DIPHENYL-METHANE DERIVATIVE, PHARMACEUTICAL COMPOSITION AND USE | Eisai Co., Ltd. (JP) | 1993-02-17 | — | — | EP | disclosed |
| US-5182301-A | Anticoagulants | EISAI CO., LTD. (JP) | 1993-01-26 | — | — | US | disclosed |
| EP-0479332-A2 | Diphenyl-methane derivative, pharmaceutical composition and use | Eisai Co., Ltd. (JP) | 1992-04-08 | — | — | EP | disclosed |
| US-5103010-A | DIPHENYLETHYLENE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND TREATMENT METHOD | EISAI CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |
| EP-0478001-A1 | Benzophenone oxime derivatives, pharmaceutical compositions and use | Eisai Co., Ltd. (JP) | 1992-04-01 | — | — | EP | disclosed |
| US-5064848-A | Anticoagulants | EISAI CO., LTD. (JP) | 1991-11-12 | — | — | US | disclosed |
| US-5034418-A | Anticoagulants | EISAI CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| US-4978767-A | ANTICOAGULANTS | EISAI CO., LTD. (JP) | 1990-12-18 | — | — | US | disclosed |
| US-4954523-A | ANTICOAGULANT | EISAI CO., LTD. (JP) | 1990-09-04 | — | — | US | disclosed |
| EP-0346943-A1 | Diphenyl-methane derivative, pharmaceutical composition and use | Eisai Co., Ltd. (JP) | 1989-12-20 | — | — | EP | disclosed |
| US-4886834-A | ANTICOAGULANTS | EISAI CO., LTD. (JP) | 1989-12-12 | — | — | US | disclosed |
| EP-0238973-A2 | Diphenyl-methane derivative, pharmaceutical composition and use | Eisai Co., Ltd. (JP) | 1987-09-30 | — | — | EP | disclosed |