Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.47 |
| ▸ | CA2 | P00918 | 5/20 | 0.47 |
| ▸ | CA9 | Q16790 | 5/20 | 0.47 |
| ▸ | CA12 | O43570 | 4/20 | 0.47 |
| ▸ | CA4 | P22748 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | QPCT | Q16769 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9516064 | 0.87 | TSHR (0.62) | CA1CA2CA9TSHRALDH1A1 | |
| SCHEMBL9516122 | 0.86 | CA1 (0.62) | CA1CA2CA9TSHRALDH1A1 | |
| SCHEMBL9517098 | 0.84 | ALDH1A1 (0.61) | CA1CA2CA9TSHRALDH1A1 | |
| SCHEMBL27535799 | 0.82 | CA1 (0.47) | CA1CA2CA9CA12CA4 | |
| SCHEMBL9517134 | 0.80 | NLRP3 (0.68) | TSHRALDH1A1MAPTNLRP3LMNA | |
| SCHEMBL9515766 | 0.79 | KMT2A (0.59) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL9515821 | 0.79 | POLB (0.49) | CA1CA2CA9CA12TSHR | |
| SCHEMBL9516791 | 0.78 | LMNA (0.54) | TSHRALDH1A1MAPTLMNATP53 | |
| SCHEMBL9519304 | 0.77 | CA1 (0.55) | CA1CA2CA9TSHRALDH1A1 | |
| SCHEMBL9518076 | 0.77 | LMNA (0.44) | CA1CA2CA9ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |