Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 6/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.47 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9516970 | 0.94 | BCL2L1 (0.48) | BCL2L1MCL1P4HTMMEN1NPC1 | |
| SCHEMBL9516250 | 0.89 | CA2 (0.46) | P4HTMNPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL9518145 | 0.86 | P4HTM (0.61) | BCL2L1MCL1P4HTM | |
| SCHEMBL9515759 | 0.84 | P4HTM (0.58) | BCL2L1MCL1P4HTMNPC1RAB9A | |
| SCHEMBL9517158 | 0.83 | NPC1 (0.46) | BCL2L1MCL1P4HTMNPC1RAB9A | |
| SCHEMBL9517102 | 0.83 | NPC1 (0.49) | BCL2L1MCL1P4HTMMEN1NPC1 | |
| SCHEMBL9515740 | 0.82 | RAB9A (0.48) | BCL2L1MCL1P4HTMMEN1NPC1 | |
| SCHEMBL9517095 | 0.82 | RAB9A (0.48) | BCL2L1MCL1P4HTMMEN1NPC1 | |
| SCHEMBL9515765 | 0.82 | HSP90AA1 (0.46) | BCL2L1MCL1P4HTMNPC1RAB9A | |
| SCHEMBL8870207 | 0.81 | CA2 (0.48) | BCL2L1MCL1P4HTMMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |