Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 6/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.48 |
| ▸ | P4HTM | Q9NXG6 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9517291 | 0.94 | BCL2L1 (0.47) | BCL2L1MCL1P4HTMKMT2AHDAC3 | |
| SCHEMBL9518145 | 0.88 | P4HTM (0.61) | BCL2L1MCL1P4HTMEGFR | |
| SCHEMBL9515759 | 0.85 | P4HTM (0.58) | BCL2L1MCL1P4HTMNPC1RAB9A | |
| SCHEMBL9516250 | 0.83 | CA2 (0.46) | P4HTMKMT2AKDM4ENPC1RAB9A | |
| SCHEMBL9517308 | 0.83 | ALDH1A1 (0.50) | BCL2L1MCL1P4HTMKMT2ANPC1 | |
| SCHEMBL9515549 | 0.82 | KDM4E (0.52) | P4HTMKMT2AKDM4ESMN1; SMN2NFKB1 | |
| SCHEMBL9515987 | 0.82 | NPC1 (0.49) | BCL2L1MCL1P4HTMKMT2AHDAC2 | |
| SCHEMBL9515532 | 0.81 | P4HTM (0.61) | BCL2L1MCL1P4HTMEGFR | |
| SCHEMBL9516137 | 0.81 | HDAC3 (0.45) | P4HTMKMT2AHDAC3HDAC1HDAC2 | |
| SCHEMBL9517102 | 0.81 | NPC1 (0.49) | BCL2L1MCL1P4HTMKMT2AHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |